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A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Location: Boston MA, Hawthorne NY, Richmond VA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07063745

Phase2, Phase3, Recruiting

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

for
Non Small Cell Lung Cancer
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT06364917

Phase2, Recruiting

A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Manahawkin NJ, Fairfax VA, Weston FL, Pittsburgh PA,
Sponsor: Wayshine Biopharm, Inc.

Sex: All

Age: 18+

Code: NCT06868485

Phase2, Recruiting

Increasing Lung Cancer Screening Uptake Among Emergency Department Patients

for
Screening Compliance, Lung Cancer (Diagnosis),
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 50 - 70+

Code: NCT07287085

Recruiting

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

for
Lung Cancer (Diagnosis), Anxiety, Depression in Adults
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT07102147

Recruiting

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Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Boston MA, Nashville TN, Peoria IL
Sponsor: Nerviano Medical Sciences

Sex: All

Age: 18+

Code: NCT06931626

Phase1, Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

for
Colon Cancer, Pancreatic Cancer, Lung Cancer (NSCLC),
Location: Boston MA, Washington D.C. DC, Fairfax VA, Durham NC,
Sponsor: Pheon Therapeutics

Sex: All

Age: 18+

Code: NCT07127874

Phase1, Recruiting

Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

for
Lung Cancer (NSCLC), Geriatric Assessment,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 65+

Code: NCT06987890

Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06218914

Phase1, Recruiting

Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT

for
Lung Cancer, Health Screening, Early Cancer Detection,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 50 - 70+

Code: NCT06910956

Recruiting

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for
Urothelial Carcinoma Bladder,
Location: New York NY, Glen Burnie MD, Miami FL, Pittsburgh PA,
Sponsor: Aktis Oncology, Inc.

Sex: All

Age: 18+

Code: NCT07020117

Phase1, Recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

for
ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC),
Location: Lake Success NY, East Brunswick NJ, Fairfax VA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18 - 70+

Code: NCT07540572

Phase1, Recruiting

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05985655

Phase1, Phase2, Recruiting

Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners

for
Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02596490

Recruiting

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

for
Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8,
Location: Newnan GA, Zion IL, Goodyear AZ, Upland CA, Corona CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07288034

Phase2, Recruiting

Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Boston MA, New York NY, Montreal, Washington D.C. DC,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT07154706

Phase3, Recruiting

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

for
Small Cell Lung Cancer, Small Cell Lung Cancer ( SCLC ),
Location: Hinsdale IL, New Lenox IL, Irvine CA, Duarte CA
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07476287

Phase2, Recruiting

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma,
Location: Toronto, Dallas TX, San Antonio TX
Sponsor: Auricula Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07148128

Phase1, Phase2, Recruiting

The SENTINL-1 Study: Evaluating Patient-Reported Outcomes of AI-Inferred Lung Cancer Risk

for
Lung Cancer
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 50 - 70+

Code: NCT07458425

Recruiting

NBTXR3 With Radiation Therapy Alone for Locally-advanced Non-small Cell Lung Cancer

for
Locally-Advanced Non-Small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07224152

Phase1, Phase2, Recruiting