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Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

for
Epstein-Barr Virus Infections, Lymphoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT03258567

Phase2, Recruiting

Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

for
Lymphoma
Location: Houston TX, San Antonio TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05676450

Recruiting

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma

for
Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05929612

Phase2, Recruiting

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

for
Non Hodgkin Lymphoma,
Location: Boston MA, New Haven CT, Durham NC, Chicago IL,
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18+

Code: NCT06116110

Recruiting

Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma

for
Follicular Lymphoma
Location: New Brunswick NJ, Miami FL, Ann Arbor MI
Sponsor: Juan P. Alderuccio, MD

Sex: All

Age: 18+

Code: NCT04998669

Phase2, Recruiting

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Digital Peer Navigation for Adolescents and Young Adults With Cancer

for
Lymphoma, Breast Cancer, Testicular Cancer, Sarcoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 40

Code: NCT06193369

Recruiting

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Miami FL
Sponsor: Florida International University

Sex: All

Age: 0 - 21

Code: NCT05857969

Phase1, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for
Locally Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Scarborough ME, Boston MA, Montreal, Philadelphia PA,
Sponsor: Turning Point Therapeutics, Inc.

Sex: All

Age: 0 - 25

Code: NCT04094610

Phase1, Phase2, Recruiting

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

for
T-cell Acute Lymphoblastic Lymphoma, T-non-Hodgkin Lymphoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 70+

Code: NCT03081910

Phase1, Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

for
Melanoma, Lymphoma, Solid Tumor, Classical Hodgkin Lymphoma,
Location: Boston MA, New York NY, Chicago IL, Fargo ND,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 17

Code: NCT02332668

Phase1, Phase2, Recruiting

Familial Investigations of Childhood Cancer Predisposition

for
Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT03050268

Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 39

Code: NCT05800210

Phase2, Recruiting

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

for
Mantle Cell Lymphoma, Non Hodgkin Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05529069

Phase2, Recruiting

Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma

for
Lymphoma, Non-Hodgkin Lymphoma, B-Cell
Location: Cleveland OH
Sponsor: Luminary Therapeutics

Sex: All

Age: 18+

Code: NCT05312801

Phase1, Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for
Hematologic Malignancy, Leukemia, Lymphoma,
Location: Cincinnati OH, Milwaukee WI, Houston TX, Aurora CO
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0 - 38

Code: NCT06131801

Recruiting

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

for
Lymphoma, Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03223610

Phase1, Phase2, Recruiting

Modified Immune Cells (CD19 CAR T Cells) and Acalabrutinib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

for
Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT04484012

Phase2, Recruiting

Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05336812

Phase2, Recruiting

A Study to Investigate Fadraciclib (CYC065), in Subjects With Advanced Solid Tumors and Lymphoma

for
Solid Tumor, Adult, Lymphoma
Location: Houston TX, Duarte CA
Sponsor: Cyclacel Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT04983810

Phase1, Phase2, Recruiting