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Active & Responsive

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for
Autoimmune Disease, Crohn Disease, Dermatomyositis,
Location: Boston MA, New Haven CT, Mineola NY, New York NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03816345

Phase1, Recruiting
Active & Responsive

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

for
EBV, HSV, VZV, HPV, CMV
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 2 - 70+

Code: NCT01011712

Recruiting
Active & ResponsiveNew

Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation

for
Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation,
Location: Boston MA, Chicago IL, Minneapolis MN, Los Angeles CA
Sponsor: Institut de Recherches Internationales Servier (I.R.I.S.)

Sex: All

Age: 12 - 17

Code: NCT07286292

Phase2, Recruiting
Active & Responsive

177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry

for
Neuroendocrine Tumors, Neuroendocrine Tumor Grade 1,
Location: Iowa City IA
Sponsor: University of Iowa

Sex: All

Age: 18+

Code: NCT06395402

Phase2, Recruiting
Active & Responsive

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for
Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma,
Location: Boston MA, New York NY, Baltimore MD,
Sponsor: Carl Allen

Sex: All

Age: 0+

Code: NCT04079179

Phase2, Recruiting

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Active & Responsive

Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT05943496

Phase1, Recruiting
Active & Responsive

Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

for
Acute Myeloid Leukemia, Chronic Myeloid Leukemia,
Location: Columbus OH, Westwood KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18 - 65

Code: NCT03533816

Phase1, Recruiting
Active & Responsive

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

for
Non-Small Cell Carcinoma of Lung, TNM Stage 4,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT03042221

Recruiting
Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase1, Phase2, Recruiting
Active & Responsive

Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder

for
Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder,
Location: New Brunswick NJ, Hillsborough NC, Columbus OH,
Sponsor: Timothy Voorhees

Sex: All

Age: 18+

Code: NCT05786040

Phase2, Recruiting
Active & Responsive

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

for
Chronic Lymphocytic Leukemia, B-cell Malignancies
Location: Florham Park NJ, Miami Beach FL, Pittsburgh PA,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT07271667

Phase2, Recruiting
Active & Responsive

The Florida ASCENT Study

for
Cancer, Food Deprivation, Food Habits, Food Selection,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT07042243

Recruiting
Active & Responsive

ME/CFS Brain Fog: Cognitive Rehabilitation Trial

for
ME/CFS,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT07523113

Recruiting
Active & Responsive

Telehealth Music Therapy for Adults With Endocrine Disorder and Depression

for
Type 1 Diabetes, Hashimoto Disease, Graves Disease,
Location: Boone NC
Sponsor: Appalachian State University

Sex: All

Age: 18 - 65

Code: NCT07413874

Recruiting
Active & Responsive

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

for
Astrocytoma, Glioblastoma, Progressive Disease
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18 - 70+

Code: NCT07560865

Phase1, Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for
Lymphoblastic Leukemia
Location: New York NY, Norfolk VA, Hershey PA, Orlando FL,
Sponsor: Tanja Andrea Gruber

Sex: All

Age: 0 - 1

Code: NCT05848687

Phase1, Phase2, Recruiting
Active & Responsive

Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for
CLL/SLL
Location: Boston MA, Charlotte NC, Jacksonville FL, Canton OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT04215809

Phase1, Recruiting
Active & Responsive

The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey

for
Cancer
Location: Rye NY
Sponsor: Lymphoma and Leukemia Society

Sex: All

Age: 18+

Code: NCT07173322

Recruiting
Active & Responsive

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

for
Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer,
Location: Hartford CT, New York NY, Englewood NJ, Florham Park NJ,
Sponsor: VM Oncology, LLC

Sex: All

Age: 18 - 70+

Code: NCT03556228

Phase1, Phase2, Recruiting