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Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia, CLL, Untreated, Front-line,
Location: Boston MA, New Hyde Park NY, Houston TX, La Jolla CA
Sponsor: Chronic Lymphocytic Leukemia Research Consortium

Sex: All

Age: 0+

Code: NCT00628238

Phase2, Recruiting

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome,
Location: Boston MA, Houston TX, Duarte CA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT03113643

Phase1, Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

for
Vulvar Diseases, HPV Infection, Vulvar HSIL,
Location: Fort Myers FL, Mayfield Heights OH, Cleveland OH,
Sponsor: Frantz Viral Therapeutics, LLC

Sex: Female

Age: 18+

Code: NCT06075264

Phase2, Recruiting

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

for
Waldenstrom Macroglobulinemia
Location: Huntsville AL, Mobile AL, Las Vegas NV,
Sponsor: BeiGene

Sex: All

Age: 18+

Code: NCT05640102

Recruiting

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia, ALL, Childhood, ALL
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18 - 39

Code: NCT03571321

Phase1, Recruiting

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Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06184321

Early_phase1, Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: New York NY, Philadelphia PA, Durham NC, Toronto,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 0+

Code: NCT04065399

Phase1, Phase2, Recruiting

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

for
Blastic Plasmacytoid Dendritic Cell Neoplasm
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04216524

Phase2, Recruiting

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12 - 70+

Code: NCT04744116

Early_phase1, Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

for
AML, ALL, MDS, MPD Withou Myelofibrosis, NHL or HL,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0 - 21

Code: NCT04644016

Phase2, Recruiting

A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis

for
Leptomeningeal Metastases
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05184816

Phase1, Recruiting

Massage Impact on Sleep in Pediatric Oncology

for
Cancer, Pediatric Cancer, Chemotherapy Effect,
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 12 - 21

Code: NCT06892158

Recruiting

CapTemY90 for Grade 2/3 NET Liver Metastases

for
Neuroendocrine Tumor Grade 2, Neuroendocrine Tumors
Location: Philadelphia PA, Miami FL, Buffalo NY, La Jolla CA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT04339036

Phase2, Recruiting

Expressive Writing for the Management of Stress in Cancer Survivors

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04776941

Recruiting

European Prospective Investigation Into Childhood Cancer

for
Acute Lymphoblastic Leukemia, Brain Tumor
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 3 - 21

Code: NCT05375617

Recruiting

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

for
B-cell Acute Lymphoblastic Leukemia, Obesity
Location: Philadelphia PA, Charlotte NC, Ann Arbor MI,
Sponsor: Etan Orgel

Sex: All

Age: 7 - 25

Code: NCT05082519

Phase2, Recruiting

Genetic Studies of Chronic Active Epstein-Barr Disease

for
Chronic Active Epstein-Barr Virus
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 1 - 70+

Code: NCT00032513

Recruiting

Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 21+

Code: NCT05054413

Recruiting

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, Buffalo NY, Chicago IL
Sponsor: Marlise Luskin, MD

Sex: All

Age: 18+

Code: NCT03595917

Phase1, Recruiting

Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT03986034

Phase2, Recruiting