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Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting
Active & Responsive

Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

for
Glioblastoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06831526

Early_phase1, Recruiting
Active & Responsive

Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

for
Glioblastoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07392957

Phase1, Phase2, Recruiting
Active & Responsive

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

for
Astrocytoma, Glioblastoma, Progressive Disease
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18 - 70+

Code: NCT07560865

Phase1, Recruiting
Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Boston MA, New Haven CT, New York NY, Montreal,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase2, Phase3, Recruiting

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Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma

for
Malignant Glioma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04771806

Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

for
High Grade Glioma, Meningioma, Embryonal Tumor, Medulloblastoma,
Location: Columbus OH, Cincinnati OH
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 4 - 39

Code: NCT05278208

Phase1, Phase2, Recruiting

CARv3-TEAM-E T Cells in Glioblastoma

for
Glioblastoma, Malignant Glioma, Recurrent Glioblastoma,
Location: Boston MA
Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All

Age: 18+

Code: NCT05660369

Phase1, Recruiting

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

for
IDH1 wt Allele, Recurrent Anaplastic Astrocytoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03896568

Phase1, Recruiting

Pilot Study Evaluating the Optimization of the ORBEYE Blue Light Filter During Fluorescence-Guided Resection of Gliomas

for
Malignant Glioma of Brain
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT04937244

Recruiting

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

for
Anaplastic Oligodendroglioma, Astrocytoma, IDH-Mutant, Grade 3,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07468136

Phase1, Phase2, Recruiting

A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

for
Adult Glioblastoma, High Grade Glioma,
Location: Washington D.C. DC, Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 4+

Code: NCT04573140

Phase1, Recruiting

T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas

for
Malignant Glioma
Location: Iowa City IA
Sponsor: John M. Buatti

Sex: All

Age: 21+

Code: NCT07447531

Recruiting

Chronic CED of TPT for Recurrent Malignant Glioma

for
Brain Tumor, Recurrent, Malignant Glioma (WHO Grade III or IV),
Location: New York NY
Sponsor: Jeffrey N. Bruce

Sex: All

Age: 18+

Code: NCT06666712

Phase1, Recruiting

Mapping of Electrical Properties in the Brain

for
Malignant Glioma
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06470711

Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

for
Malignant Glioma
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 21

Code: NCT05099003

Phase1, Phase2, Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

for
Malignant Glioma of Brain, Astrocytoma, Malignant Astrocytoma,
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT05686798

Phase1, Recruiting

Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

for
Diffuse Glioma, Malignant Glioma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05717153

Early_phase1, Recruiting

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

for
Malignant Glioma
Location: Jacksonville FL, Phoenix AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05030298

Phase1, Recruiting

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

for
Recurrent Malignant Glioma, Recurrent WHO Grade 3 Glioma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06964737

Phase1, Recruiting