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Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

for
Glioblastoma, IDH-wildtype, Glioblastoma,
Location: Providence RI, New York NY, Durham NC, Cleveland OH,
Sponsor: Orbus Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05879367

Phase1, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

Familial Investigations of Childhood Cancer Predisposition

for
Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT03050268

Recruiting

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype,
Location: New York NY, Chicago IL, Houston TX, Dallas TX,
Sponsor: Debiopharm International SA

Sex: All

Age: 18+

Code: NCT05765812

Phase1, Phase2, Recruiting

Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT05423210

Early_phase1, Recruiting

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Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT00083512

Recruiting

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for
Glioblastoma
Location: Sherbrooke, Montreal, Ottawa, Toronto, Hamilton,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06556563

Phase3, Recruiting

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

for
Glioblastoma Multiforme, Astrocytoma, Grade III
Location: Houston TX
Sponsor: David Baskin MD

Sex: All

Age: 18+

Code: NCT03596086

Phase1, Phase2, Recruiting

Studying Health Outcomes After Treatment in Patients With Retinoblastoma

for
Retinoblastoma, Cancer Survivor, Biological Sibling,
Location: Philadelphia PA, Toronto, Cincinnati OH, Nashville TN,
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 0+

Code: NCT03932786

Recruiting

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

for
Glioblastoma, Gliosarcoma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06934889

Phase1, Recruiting

MRI Predictors of Response to Tumor Treating Fields

for
Glioblastoma Multiforme
Location: Brooklyn NY
Sponsor: New York Presbyterian Brooklyn Methodist Hospital

Sex: All

Age: 18+

Code: NCT03642080

Recruiting

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

for
EGFR Gene Mutation, Glioblastoma,
Location: San Francisco CA
Sponsor: Hideho Okada, MD, PhD

Sex: All

Age: 18+

Code: NCT06186401

Phase1, Recruiting

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

for
Glioblastoma, Glioblastoma, IDH-wildtype,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06146725

Recruiting

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

for
Cervical Cancer, Breast Cancer, Colon Cancer, NSCLC,
Location: Glen Burnie MD, Lexington KY, Omaha NE
Sponsor: Orano Med Theranostics, SAS

Sex: All

Age: 18+

Code: NCT05283330

Phase1, Recruiting

Study of Pembrolizumab and M032 (NSC 733972)

for
Glioblastoma Multiforme, Anaplastic Astrocytoma, Gliosarcoma
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT05084430

Phase1, Phase2, Recruiting

Sacituzumab Govitecan in Recurrent Glioblastoma

for
Recurrent Glioblastoma
Location: Cleveland OH, Austin TX, San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 18+

Code: NCT04559230

Phase2, Recruiting

A Study to Give Treatment Inside the Eye to Treat Retinoblastoma

for
Bilateral Retinoblastoma, Childhood Intraocular Retinoblastoma,
Location: Montreal, Durham NC, Akron OH, Cleveland OH, Atlanta GA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 18

Code: NCT05504291

Phase2, Recruiting

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

for
Glioblastoma, Recurrent Glioblastoma, Brain Tumor
Location: Boston MA
Sponsor: Ugonma Chukwueke

Sex: All

Age: 18+

Code: NCT06552260

Early_phase1, Recruiting

D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients

for
Newly Diagnosed MGMT Unmethylated Glioblastoma
Location: Durham NC
Sponsor: Darell Bigner

Sex: All

Age: 18+

Code: NCT05734560

Phase1, Phase2, Recruiting

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

for
Newly Diagnosed Glioblastoma
Location: New York NY, Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06816927

Phase2, Recruiting