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Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Springfield MA, Saint Johnsbury VT, Lebanon NH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase2, Recruiting
Active & Responsive

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

for
Cancer, Breast Cancer, Lung Cancer, Colon Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03702309

Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Scarborough ME, Worcester MA, Hartford CT, Norwalk CT,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & ResponsiveNew

A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

for
Clinical Stage 0 Cutaneous Melanoma AJCC v8,
Location: Philadelphia PA, Pittsburgh PA, Knoxville TN,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT07621614

Recruiting
Active & ResponsiveNew

Phase I/IIa Dose Finding Study of Triplet Regimen of Relatlimab Ipilimumab and NIvolumab in First Line Therapy of Metastatic Melanoma (TRINITY)

for
Melanoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06683755

Phase1, Phase2, Recruiting

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Active & ResponsiveNew

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

for
Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma,
Location: Scottsdale AZ
Sponsor: VM Discovery, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07636785

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma

for
Uveal Melanoma
Location: Philadelphia PA, Toronto, Nashville TN, Scottsdale AZ
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07804186

Phase3, Recruiting
Active & Responsive

Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi

for
Melanoma
Location: Pittsburgh PA
Sponsor: John Kirkwood

Sex: All

Age: 18+

Code: NCT06599619

Recruiting
Active & Responsive

DermaSensor Postmarket Surveillance Study

for
Melanoma, Skin
Location: Morehead City NC, New Smyrna Beach FL
Sponsor: DermaSensor, Inc.

Sex: All

Age: 40+

Code: NCT06666790

Recruiting
Active & Responsive

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

for
Uveal Melanoma, Cutaneous Melanoma, BAP1 Gene Mutation,
Location: Columbus OH
Sponsor: Mohamed Abdel-Rahman

Sex: All

Age: 0+

Code: NCT04792463

Recruiting
Active & Responsive

In Vivo Liquid Biopsy of Melanoma (Cytophone)

for
Melanoma, Circulating Tumor Cells, Metastatic Melanoma,
Location: Madison WI
Sponsor: Cytoastra

Sex: All

Age: 18 - 70+

Code: NCT06488365

Recruiting
Active & Responsive

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

for
Metastatic Melanoma, Liver Metastases
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT07281924

Phase1, Phase2, Recruiting
Active & Responsive

The Florida ASCENT Study

for
Cancer, Food Deprivation, Food Habits, Food Selection,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT07042243

Recruiting
Active & Responsive

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

for
Melanoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06961357

Phase1, Phase2, Recruiting
Active & Responsive

Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma, Uveal Melanoma, Metastatic,
Location: Nashville TN, Denver CO, Scottsdale AZ
Sponsor: Novelwise Pharmaceutical Corporation

Sex: All

Age: 18+

Code: NCT07136181

Phase1, Phase2, Recruiting
Active & Responsive

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

for
Advanced Unresectable Melanoma, Metastatic Melanoma
Location: San Francisco CA
Sponsor: Kevin Kim, MD

Sex: All

Age: 18+

Code: NCT07237100

Phase2, Recruiting
Active & Responsive

Sitagliptin With Pembro in RCC and Melanoma

for
Advanced Renal Cell Carcinoma, Advanced Melanoma
Location: Iowa City IA
Sponsor: Fernando Maciel Barbosa

Sex: All

Age: 18 - 70+

Code: NCT07634380

Phase1, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, New York NY,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase3, Recruiting
Active & Responsive

Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma

for
Melanoma, Unresectable Melanoma
Location: Boston MA, New York NY, Los Angeles CA
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 70+

Code: NCT05428007

Phase2, Recruiting
Active & Responsive

Evaluation of Hypoxia in Primary Melanoma

for
Melanoma
Location: Pittsburgh PA
Sponsor: Yana Najjar

Sex: All

Age: 18+

Code: NCT06831071

Recruiting