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AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

for
Advanced Melanoma and Normal or Impaired, Advanced Melanoma
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07027488

Phase1, Recruiting

A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

for
Malignant Melanoma
Location: Hackensack NJ, Fairfax VA, Toronto, Brampton,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06961006

Phase2, Recruiting

Integrated Cancer Repository for Cancer Research

for
Pancreatic Cancer, Thyroid Cancer, Lung Cancer,
Location: Manchester CT, Holyoke MA, Glens Falls NY, Utica NY,
Sponsor: University of Nebraska

Sex: All

Age: 19 - 70+

Code: NCT02012699

Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

In Vivo Real-time Detection of Circulating Melanoma Cells

for
Melanoma
Location: Little Rock AR
Sponsor: University of Arkansas

Sex: All

Age: 18 - 70+

Code: NCT01776905

Recruiting

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A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for
Melanoma, Non-small Cell Lung Cancer,
Location: Fairfax VA, Pittsburgh PA, Grand Rapids MI, St Louis MO,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07115043

Phase1, Phase2, Recruiting

IDOV-Immune for Advanced Solid Tumors

for
Colorectal Cancer, Pancreatic Cancer, Melanoma, Ovarian Cancer,
Location: St Louis MO, Houston TX, San Antonio TX
Sponsor: ViroMissile, Inc.

Sex: All

Age: 18+

Code: NCT06910657

Phase1, Recruiting

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04693377

Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

for
Breast Cancer, Colorectal Cancer, Pancreas Cancer,
Location: Kingston, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05403177

Recruiting

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Melanoma, HNSCC, Sarcoma, Squamous Cell Carcinoma,
Location: Boston MA, Fairfax VA, Pittsburgh PA, Dallas TX
Sponsor: ImmVira Pharma Co. Ltd

Sex: All

Age: 18+

Code: NCT04370587

Phase1, Phase2, Recruiting

Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

for
Melanoma
Location: Camden NJ, Jacksonville FL, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04594187

Phase2, Recruiting

Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!)

for
Breast Cancer, Melanoma, Gastrointestinal Neuroendocrine Tumor
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05196087

Recruiting

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

for
Ovarian Cancer, Melanoma, Triple Negative Breast Cancer,
Location: Fairfax VA, Dallas TX
Sponsor: Hefei TG ImmunoPharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT05746897

Phase1, Recruiting

FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma

for
Advanced Melanoma
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT06472661

Early_phase1, Recruiting

Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma

for
Melanoma Stage III, Melanoma Stage IV, BRAF V600 Mutation
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT04741997

Early_phase1, Recruiting

Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases

for
Clinical Stage IV Cutaneous Melanoma AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05026983

Phase2, Recruiting

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

for
Cancer, Melanoma Stage III, Melanoma Stage IV,
Location: New York NY, Morristown NJ, Weston FL, Pittsburgh PA,
Sponsor: Krystal Biotech, Inc.

Sex: All

Age: 18+

Code: NCT05970497

Phase1, Phase2, Recruiting

Video Education With Result Dependent dIsclosure

for
Genetic Testing, Breast Cancer, Ovarian Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05225428

Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for
Oncology, MEK Mutation, RAF Gene Mutation,
Location: New York NY, Fairfax VA, Buffalo NY, Pittsburgh PA,
Sponsor: Nested Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06326411

Phase1, Recruiting

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

for
Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC)
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT04844528

Phase2, Recruiting