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Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

for
Metastatic Melanoma, BRAF Gene Mutation
Location: Easton PA, Lexington KY, Nashville TN
Sponsor: Rina Plattner

Sex: All

Age: 18+

Code: NCT04903119

Phase1, Recruiting

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

for
Tumor Skin, Metastatic Melanoma, Melanoma, Lung Cancer,
Location: New York NY, Pittsburgh PA, Orlando FL, Louisville KY,
Sponsor: Obsidian Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06060613

Phase1, Phase2, Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

for
Metastatic Malignant Solid Neoplasm, Metastatic Melanoma,
Location: Duarte CA, Los Angeles CA, Stanford CA
Sponsor: Anusha Kalbasi

Sex: All

Age: 18 - 70+

Code: NCT04119024

Phase1, Recruiting

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06075524

Recruiting

Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma

for
Melanoma
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06365619

Phase2, Recruiting

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for
Colorectal Carcinoma, Endometrial Carcinoma, Melanoma,
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 30

Code: NCT04851119

Phase1, Phase2, Recruiting

Neurocutaneous Melanocytosis Registry

for
Cutaneous Melanocytic Neoplasm,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT04548817

Recruiting

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

for
Melanoma (Skin), Skin Cancer, Advanced Melanoma
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06298734

Recruiting

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

for
Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer,
Location: Pittsburgh PA
Sponsor: Dan Zandberg

Sex: All

Age: 18+

Code: NCT04114136

Phase2, Recruiting

Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients

for
Melanoma, Melanoma Stage III, Melanoma Stage IV,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT06199713

Recruiting

Rural Adult and Youth Sun Protection Study

for
Melanoma (Skin), Skin Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 3 - 7

Code: NCT06439979

Recruiting

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

for
Melanoma, Squamous Cell Carcinoma of Head and Neck
Location: Boston MA, New Haven CT, Richmond VA
Sponsor: IO Biotech

Sex: All

Age: 18+

Code: NCT05280314

Phase2, Recruiting

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

for
Locally Advanced Alveolar Soft Part Sarcoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06066138

Phase1, Recruiting

Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC

for
Non-small Cell Lung Cancer(NSCLC),
Location: Fairfax VA
Sponsor: LG Chem

Sex: All

Age: 18+

Code: NCT06332755

Phase1, Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, Hackensack NJ,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT06112314

Phase3, Recruiting

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Mineola NY, New York NY, Baltimore MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05896839

Phase1, Phase2, Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

for
Pancreatic Cancer, Renal Cell Cancer, Breast Cancer, Melanoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02830724

Phase1, Phase2, Recruiting

Cryoablation+Ipilimumab+Nivolumab in Melanoma

for
Metastatic Melanoma, Skin Cancer
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05779423

Phase2, Recruiting

Naltrexone and Propranolol Combined With Immunotherapy

for
Advanced Melanoma
Location: New Brunswick NJ
Sponsor: Sarah Weiss

Sex: All

Age: 18+

Code: NCT05968690

Phase1, Recruiting

Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

for
Advanced Melanoma, Metastatic Melanoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05629546

Phase1, Recruiting