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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma,
Location: East Brunswick NJ, Philadelphia PA, York PA,
Sponsor: Guardant Health, Inc.

Sex: All

Age: 18+

Code: NCT05059444

Recruiting

Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

for
Muscle-Invasive Bladder Carcinoma,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06529822

Phase1, Recruiting

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

for
Unresectable Melanoma, Metastatic Melanoma, Ocular Melanoma
Location: Chapel Hill NC, Nashville TN, Denver CO
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT06940739

Phase1, Phase2, Recruiting

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

for
Gastrointestinal Stromal Tumors, Small-cell Lung Cancer,
Location: Cleveland OH, Ann Arbor MI, Houston TX, Portland OR
Sponsor: Novelty Nobility, Inc.

Sex: All

Age: 18+

Code: NCT06805825

Phase1, Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

for
NSCLC, HNSCC, Melanoma, Metastatic Cancer, Advanced Solid Tumor,
Location: Pittsburgh PA, Irvine CA
Sponsor: CJ Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05877430

Phase1, Phase2, Recruiting

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A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

for
Unresectable Melanoma, Metastatic Melanoma,
Location: New York NY, Miami FL, Pittsburgh PA, Orlando FL,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT05361174

Phase1, Phase2, Recruiting

Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma

for
Clinical Stage I Cutaneous Melanoma AJCC v8,
Location: Columbus OH
Sponsor: Carlo Contreras

Sex: All

Age: 18 - 70+

Code: NCT04697576

Phase1, Recruiting

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

for
Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Tampa FL
Sponsor: Memgen, Inc.

Sex: All

Age: 18+

Code: NCT05076760

Phase1, Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

Intravenous Iron in Combination With Standard of Care Immunotherapy in Melanoma

for
Anemia, Iron Deficiency, Melanoma
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT06508827

Phase2, Recruiting

Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma

for
Sinonasal Melanoma, Anorectal Melanoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05546827

Phase2, Recruiting

A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients

for
Melanoma
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT01638676

Phase1, Phase2, Recruiting

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma
Location: New Hyde Park NY, Tampa FL, Chicago IL, Los Angeles CA
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06121180

Phase2, Recruiting

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for
Advanced Melanoma
Location: Providence RI, Lebanon NH, Lake Success NY,
Sponsor: Replimune, Inc.

Sex: All

Age: 12+

Code: NCT06264180

Phase3, Recruiting

Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07276386

Phase2, Recruiting

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for
Melanoma (Skin Cancer),
Location: Lake Success NY, Fairfax VA, Detroit MI, Cincinnati OH,
Sponsor: Aminex Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07287917

Phase1, Phase2, Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase2, Recruiting

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

for
Melanoma
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 55+

Code: NCT07704918

Recruiting

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for
Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer,
Location: Orange City FL, Clermont FL, Detroit MI, Atlanta GA,
Sponsor: Inhibrx Biosciences, Inc

Sex: All

Age: 18+

Code: NCT04198766

Phase1, Phase2, Recruiting

Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions

for
Melanoma (Skin Cancer)
Location: Chicago IL, Salt Lake City UT
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT07556380

Recruiting