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Investigating Real-Time Immunotherapy Symptoms Study

for
Cancer, Melanoma (Skin Cancer), Immunotherapy
Location: Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: All

Age: 18+

Code: NCT07280715

Recruiting

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

for
Brain Cancer, Brain Metastases, Melanoma, Lung Cancer,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT04899908

Phase2, Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

for
Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07628634

Early_phase1, Recruiting

IL-17 Blockade to Decrease irAEs (REPLAY)

for
Metastatic Melanoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07237594

Phase1, Recruiting

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for
Advanced NRAS-Mutant Melanoma,
Location: Boston MA, New York NY, Fairfax VA, Grand Rapids MI,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07584226

Phase1, Recruiting

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Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

for
Advanced Biliary Tract Carcinoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07405086

Recruiting

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

for
Breast Cancer (Triple Negative Breast Cancer (TNBC)),
Location: Nashville TN
Sponsor: Jessica Mezzanotte Sharpe

Sex: All

Age: 18+

Code: NCT07555210

Recruiting

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

for
Non-Small-Cell Lung, Esophageal Cancer, Cutaneous Melanoma
Location: New Haven CT, Trumbull CT, Fairfax VA, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07519655

Phase1, Recruiting

Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

for
Breast Cancer, Lung Cancer, Melanoma, Gynecologic Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07524114

Recruiting

A Study of BI 3810944 in Patients With Advanced Cancer

for
Solid Tumours, Melanoma
Location: Louisville KY, Nashville TN
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07224425

Phase1, Recruiting

Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver

for
Uveal Melanoma
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07364474

Recruiting

Stereotactic Ablative Radiotherapy (XRT) and Immunotherapy for Oligometastatic Extracranial Melanoma

for
Melanoma Metastatic
Location: Toronto
Sponsor: Melanoma Institute Australia

Sex: All

Age: 18+

Code: NCT06767306

Phase2, Recruiting

DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

for
Refractory Melanoma
Location: Boston MA, Morristown NJ, Chapel Hill NC, Birmingham AL,
Sponsor: Diakonos Oncology Corporation

Sex: All

Age: 18+

Code: NCT07288112

Phase1, Phase2, Recruiting

Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically

for
Non-Melanoma Skin Cancer (NMSC), Benign Skin Growth
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18+

Code: NCT07201376

Recruiting

Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients

for
Melanoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07379138

Recruiting

A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

for
Melanoma, Metastatic Melanoma, Advanced Solid Tumor,
Location: La Jolla CA
Sponsor: Replimune Inc.

Sex: All

Age: 18+

Code: NCT06887348

Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Frederick MD, St Louis MO, Springfield MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

Promoting Immunotherapy Efficacy With Low-Dose Liver RT

for
Low-Dose Liver Radiation (LD-LRT), Non Small Cell Lung Cancer,
Location: Cincinnati OH
Sponsor: Jordan Kharofa

Sex: All

Age: 18+

Code: NCT07225036

Recruiting

Sample Collection for Ongoing Research and Product Evaluation Study

for
Breast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer,
Location: Austin TX
Sponsor: Natera, Inc.

Sex: All

Age: 18+

Code: NCT07318051

Recruiting

Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

for
Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07215988

Recruiting