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Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases

for
Metastatic Colorectal Cancer, Liver Metastases
Location: New York NY
Sponsor: Dan Feng

Sex: All

Age: 18+

Code: NCT07277322

Phase1, Phase2, Recruiting

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

for
Metastatic Colorectal Cancer, Hepatocellular Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06553885

Phase2, Recruiting

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for
Solid Tumor, Adult, Metastatic Breast Cancer,
Location: Boston MA, New York NY, Tampa FL, Indianapolis IN,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06625775

Phase1, Recruiting

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Boston MA, New Haven CT, New York NY, Tampa FL,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06917079

Phase1, Recruiting

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

for
Metastatic Colorectal Cancer, Metastatic Pancreatic Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT01174121

Phase2, Recruiting

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Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

for
Metastatic Colorectal Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06149481

Phase1, Phase2, Recruiting

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Trenton NJ, Montreal, Baltimore MD, Washington D.C. DC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06792695

Phase2, Recruiting

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

for
Metastatic Colorectal Cancer (Mcrc),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05286814

Phase2, Recruiting

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

for
Advanced or Metastatic Colorectal Cancer
Location: New York NY, Ottawa, Toronto, Ann Arbor MI,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05379595

Phase1, Phase2, Recruiting

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for
Advanced Cancer, Metastatic Cancer, Ovarian Cancer,
Location: Lake Success NY, Philadelphia PA, East Syracuse NY,
Sponsor: Artios Pharma Ltd

Sex: All

Age: 18+

Code: NCT04657068

Phase1, Phase2, Recruiting

A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC)

for
Metastatic Colorectal Cancer
Location: Madison WI, Omaha NE, Houston TX
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07416552

Phase1, Recruiting

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

for
Metastatic Colorectal Cancer
Location: White Plains NY, Newport News VA, Ottawa,
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT07549412

Phase3, Recruiting

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

for
Ras-mutated Metastatic Colorectal Cancer, mCRC,
Location: New Brunswick NJ, Florham Park NJ, Canton OH,
Sponsor: Oncolytics Biotech

Sex: All

Age: 18+

Code: NCT07446322

Phase2, Recruiting

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT05854498

Phase2, Recruiting

Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

for
Metastatic Colorectal Cancer, Advanced Colorectal Cancer
Location: Newark DE, Kingwood TX
Sponsor: Riboscience, LLC.

Sex: All

Age: 18+

Code: NCT06824064

Phase2, Recruiting

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer (CRC)
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT07042685

Phase2, Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

for
Untreated, Unresectable, or Metastatic Colorectal Cancer
Location: Shirley NY, Sherbrooke, Mineola NY, Lake Success NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07221357

Phase2, Phase3, Recruiting

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer (CRC)
Location: Providence RI, Norwich CT, Hartford CT, New Haven CT,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT07228832

Phase3, Recruiting

Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

for
Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients,
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT07167446

Early_phase1, Recruiting

Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer

for
Phase 1, SAR445877, FOlfox6, Bevacizimab, First Line Treatment,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07500298

Phase1, Recruiting