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A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for
Metastatic Colorectal Cancer
Location: Port Jefferson Station NY, New Haven CT,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT04929223

Phase1, Recruiting
Featured

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Boston MA, New Haven CT, Montreal, Fairfax VA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06820463

Phase2, Recruiting
Active & ResponsiveNew

Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

for
Colorectal Cancer, Metastatic Colorectal Cancer (CRC)
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT07759921

Recruiting
Active & Responsive

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for
Intestinal Neoplasms, Gastrointestinal Neoplasms,
Location: Topsham ME, Westbrook ME, Boston MA, Newton MA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222800

Phase3, Recruiting
Active & Responsive

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

for
Colorectal Cancer Screening, Colorectal Cancer Metastatic,
Location: Morrisville NC
Sponsor: Mainz Biomed

Sex: All

Age: 18+

Code: NCT06864338

Recruiting

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Active & ResponsiveNew

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

for
Left-sided Colorectal Cancer
Location: Savannah GA, Warner Robins GA, Indianapolis IN,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07702032

Phase3, Recruiting
Active & Responsive

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for
Colorectal Cancer, Colorectal Cancer (CRC),
Location: Fairfax VA, Jacksonville FL, Atlanta GA,
Sponsor: Cartography Biosciences

Sex: All

Age: 18+

Code: NCT07321106

Phase1, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, Non-Small Cell Lung,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06682793

Phase1, Phase2, Recruiting
Active & ResponsiveNew

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

for
Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma,
Location: Scottsdale AZ
Sponsor: VM Discovery, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07636785

Phase1, Phase2, Recruiting
Active & ResponsiveNew

Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver Metastasis

for
Colorectal Adenocarcinoma Metastatic in the Liver,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07764497

Phase2, Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase1, Phase2, Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

for
Metastatic Colorectal Adenocarcinoma,
Location: Baltimore MD, Washington D.C. DC, Atlanta GA, Aurora CO
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07147231

Phase1, Phase2, Recruiting
Active & Responsive

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Norwich CT, Fairfax VA, Nashville TN, Saint Paul MN,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07397338

Phase1, Phase2, Recruiting
Active & Responsive

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

for
Castration-Resistant Prostate Cancer (CRPC), Colorectal Cancer,
Location: Dothan AL, Grand Rapids MI, Omaha NE
Sponsor: Radiopharm Theranostics, Ltd

Sex: All

Age: 18+

Code: NCT07189871

Phase1, Phase2, Recruiting
Active & Responsive

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor Malignancies, Colorectal Carcinoma,
Location: Philadelphia PA, Fairfax VA, Orlando FL,
Sponsor: Tasca Therapeutics

Sex: All

Age: 18+

Code: NCT07030257

Phase1, Phase2, Recruiting
Active & Responsive

Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC

for
Colorectal Carcinoma Metastatic in the Liver
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT06555133

Phase2, Recruiting
Active & Responsive

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for
Non-small Cell Lung Cancer, Histiocytic Neoplasm, Histiocytosis,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT05786924

Phase1, Phase2, Recruiting
Active & Responsive

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm,
Location: Boston MA, New York NY, Toronto, Hamilton, Tampa FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07114601

Phase1, Recruiting
Active & Responsive

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

for
Prostate Cancer Castration-resistant Prostate Cancer,
Location: East Brunswick NJ, Fairfax VA, Grand Rapids MI,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT07145255

Phase1, Phase2, Recruiting