Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease
for
Refractory Metastatic Colorectal Cancer
Location: Tampa FL, New Orleans LA, Fairway KS, Salt Lake City UT,
Sponsor: Delcath Systems Inc.
Sex: All
Age: 18+
Code: NCT06607458
Phase2, Recruiting
Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer
for
Metastatic Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06959550
Phase2, Recruiting
Trial of ProAgio in Advanced/Metastatic Colorectal Cancer
for
Advanced Colorectal Cancer, Metastatic Colorectal Cancer
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham
Sex: All
Age: 19+
Code: NCT06867822
Phase1, Recruiting
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
for
Metastatic Colorectal Cancer
Location: New Haven CT, Cleveland OH, Grand Rapids MI, Houston TX
Sponsor: BioNTech SE
Sex: All
Age: 18+
Code: NCT07079631
Phase1, Phase2, Recruiting
5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer
for
Metastatic Colorectal Cancer (CRC)
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute
Sex: All
Age: 18+
Code: NCT06887218
Phase2, Recruiting
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Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial
for
Colorectal Cancer, Metastatic Colon Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute
Sex: All
Age: 18 - 50
Code: NCT06202183
Recruiting
Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy
for
Metastatic Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT05985954
Phase1, Recruiting
A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations
for
Metastatic Colorectal Cancer, KRAS G12C Mutations
Location: Boston MA, Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06412198
Phase1, Phase2, Recruiting
Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis
for
Metastatic Colorectal Cancer
Location: Montreal
Sponsor: Alethia Biotherapeutics
Sex: All
Age: 18+
Code: NCT06225843
Phase2, Recruiting
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation