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Active & Responsive

Phenotypic Classification of FMR With CMR

for
Nonischemic Congestive Cardiomyopathy,
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18+

Code: NCT05965258

Recruiting
Active & Responsive

AMEND TS Early Feasibility Study

for
Symptomatic Functional MR 3 or Greater
Location: New York NY, Indianapolis IN, Houston TX,
Sponsor: Valcare Medical Ltd.

Sex: All

Age: 21+

Code: NCT06951672

Recruiting
Active & Responsive

Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

for
Left Ventricular Systolic Dysfunction
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06770062

Recruiting
New

EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)

for
Mitral Regurgitation
Location: Atlanta GA
Sponsor: Polares Medical SA

Sex: All

Age: 21+

Code: NCT07517588

Recruiting
New

Use of Force Feedback Instruments With the da Vinci Surgical System, Model IS5000 for Mitral Valve Repair

for
Mitral Regurgitation (MR)
Location: New York NY, Atlanta GA, Spokane WA
Sponsor: Intuitive Surgical

Sex: All

Age: 22+

Code: NCT07655505

Recruiting

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New

Effects of VALsartan On atRIAl Mitral Regurgitation (VALORIA) - Pilot

for
Atrial Functional Mitral Regurgitation
Location: Quebec
Sponsor: Jonathan Beaudoin

Sex: All

Age: 18 - 70+

Code: NCT07539298

Phase2, Phase3, Recruiting
New

FIH ITA Study - Vesalius TMVr System for Symptomatic Degenerative Mitral Regurgitation

for
Degenerative Mitral Regurgitation
Location: Vancouver
Sponsor: Vesalius Cardiovascular Inc.

Sex: All

Age: 19+

Code: NCT07470788

Recruiting

An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

for
Mitral Regurgitation
Location: Boston MA, New York NY, Charleston SC, Atlanta GA,
Sponsor: HighLife SAS

Sex: All

Age: 18+

Code: NCT04029337

Recruiting

Use of Phenylephrine for Assessment of Mitral Regurgitation Severity

for
Mitral Regurgitation
Location: New York NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 18+

Code: NCT04500899

Phase1, Phase2, Recruiting

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for
Functional Mitral Regurgitation, Heart Failure,
Location: Boston MA, New York NY, Edison NJ, Poughkeepsie NY,
Sponsor: Cardiac Dimensions, Inc.

Sex: All

Age: 18+

Code: NCT03142152

Recruiting

Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation

for
Mitral Regurgitation, Aortic Regurgitation
Location: Morristown NJ
Sponsor: Atlantic Health System

Sex: All

Age: 18+

Code: NCT04038879

Recruiting

Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

for
Atrial Functional Mitral Regurgitation, Mitral Insufficiency
Location: Bronx NY, Toronto
Sponsor: University Hospital of Cologne

Sex: All

Age: 18+

Code: NCT06911099

Recruiting

Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease

for
Aortic Regurgitation, Mitral Regurgitation, Aortic Stenosis
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18 - 70+

Code: NCT06780241

Recruiting

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

for
Cardiogenic Shock, Mitral Regurgitation
Location: Ottawa, Rochester MN
Sponsor: Ottawa Heart Institute Research Corporation

Sex: All

Age: 18+

Code: NCT05298124

Recruiting

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

for
Mitral Regurgitation, Mitral Valve Disease,
Location: Boston MA, Quebec, New York NY, Morristown NJ, Toronto,
Sponsor: Universitätsklinikum Hamburg-Eppendorf

Sex: All

Age: 18+

Code: NCT04688190

Recruiting

Serotonin Receptor Blockers in Ischemic Mitral Regurgitation

for
Ischemic Mitral Regurgitation
Location: Quebec
Sponsor: Laval University

Sex: All

Age: 18 - 70+

Code: NCT05469165

Phase2, Recruiting

Cephea Early Feasibility Study

for
Mitral Regurgitation
Location: The Bronx NY, New York NY, Norfolk VA, Pittsburgh PA,
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT05061004

Recruiting

Structural Mitral Valve Project

for
Mitral Regurgitation
Location: Kingston
Sponsor: Queen's University

Sex: All

Age: 18+

Code: NCT05678868

Recruiting

MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR

for
Mitral Regurgitation, Heart Failure,
Location: Montreal
Sponsor: Montreal Heart Institute

Sex: All

Age: 18+

Code: NCT03705312

Recruiting

Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry

for
Mitral Regurgitation
Location: New York NY
Sponsor: Universitätsklinikum Hamburg-Eppendorf

Sex: All

Age: 18+

Code: NCT05332782

Recruiting