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Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma

for
Multiple Myeloma
Location: Iowa City IA
Sponsor: Christopher Strouse

Sex: All

Age: 18+

Code: NCT07581704

Phase1, Recruiting

A Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex in Participants With Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma

for
Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma,
Location: Fort Wayne IN
Sponsor: Grifols Biologicals, LLC

Sex: All

Age: 18+

Code: NCT07582432

Phase3, Recruiting

A Cognitive Training Intervention for Improving Cognitive and Neurological Outcomes in Patients Undergoing Treatment for Relapsed or Refractory Multiple Myeloma or B-cell Non-Hodgkin Lymphoma

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07609030

Recruiting

DC/MM Fusion Vaccine With BCMA CAR-T in R/R MM

for
Multiple Myeloma, Refractory Multiple Myeloma,
Location: Boston MA
Sponsor: David Avigan

Sex: All

Age: 18+

Code: NCT07377435

Phase1, Recruiting

Halt Aging in Survivors of Blood Cancers

for
Hematological Malignancy, Leukemia, Lymphoid Leukemia,
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 50+

Code: NCT07292272

Recruiting

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A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

for
Multiple Myeloma
Location: Norwich CT, Bethesda MD, Fort Myers FL, Macon GA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07227311

Phase2, Recruiting

A Study of Voice as a Way to Monitor for Side Effects in People Receiving CAR T-Cell Therapy

for
Non-hodgkin Lymphoma, Multiple Myeloma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07249528

Recruiting

A Phase 2 Study of Radiotherapy-induced Immune Priming to Enhance Elranatamab (Elra) in Relapsed Refractory Multiple Myeloma (RRMM) With Extramedullary Disease (EMD) and Paramedullary Disease (PMD) "PRIME-EMD-PMD"

for
Phase 2, Radiotherapy-Induced Immune Priming, Elranatamab,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT07382739

Phase2, Recruiting

Mezigdomide and Talquetamab in Relapsed and Refractory Multiple Myeloma

for
Relapsed Refractory Multiple Myeloma (RRMM)
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07032714

Phase1, Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Norfolk VA, Fairfax VA, Atlanta GA, Nashville TN,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07266441

Phase2, Recruiting

ELISA in Relapsed/Refractory MM

for
Relapsed Refractory Multiple Myeloma (RRMM),
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06832865

Phase2, Recruiting

A Study of Elranatamab and Cyclophosphamide in People With Multiple Myeloma

for
Multiple Myeloma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07454382

Phase2, Recruiting

Response-Based Dose Reduction of Linvoseltamab in the Treatment of Relapsed, Refractory, or Triple-Class Relapsed/Refractory Multiple Myeloma

for
Recurrent Multiple Myeloma, Refractory Multiple Myeloma
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07181941

Phase1, Phase2, Recruiting

Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma

for
Multiple Myeloma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07200102

Phase1, Recruiting

Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell Transplant

for
Multiple Myeloma, Plasma Cell Leukemia
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT05405387

Phase2, Recruiting

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Halifax, Farmington CT, New Haven CT, Mineola NY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07258511

Phase3, Recruiting

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

for
Multiple Myeloma, Secondary Immunodeficiency
Location: Albany NY, Montreal, Baltimore MD, Detroit MI,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06980480

Phase3, Recruiting

A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for
Multiple Myeloma
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07225738

Recruiting

A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

for
Multiple Myeloma (MM)
Location: New York NY, Brooklyn NY, Baltimore MD, Durham NC,
Sponsor: C4 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07280013

Phase1, Recruiting

Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients With Extramedullary Disease

for
Extramedullary Disease in Multiple Myeloma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06627751

Phase2, Recruiting