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Study of Cannabidiol in Sanfilippo Syndrome

for
Sanfilippo Syndrome, Mucopolysaccharidosis III
Location: Torrance CA
Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Sex: All

Age: 4+

Code: NCT06333041

Phase2, Phase3, Recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06434064

Phase2, Recruiting

Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma

for
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05363111

Phase1, Recruiting

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

for
Clinical Stage III Gastric Cancer AJCC v8,
Location: Houston TX
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06364410

Phase1, Recruiting

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

for
Stage III Lung Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04892953

Phase2, Recruiting

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Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

for
Central Nervous System Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05011045

Recruiting

Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma

for
Melanoma Stage III, Melanoma Stage IV, BRAF V600 Mutation
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT04741997

Early_phase1, Recruiting

Elranatamab Post Cilta-cel in Patients With Clinical High Risk Relapsed Myeloma

for
Myeloma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06947083

Phase2, Recruiting

Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

for
Advanced Pancreatic Adenocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06454383

Phase1, Recruiting

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

for
Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma,
Location: Boston MA, Stoneham MA, Westerly RI, Waterford CT,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT04566328

Phase3, Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

for
Stage III Hepatocellular Carcinoma AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03942328

Phase1, Phase2, Recruiting

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

for
Stage III Hepatocellular Carcinoma AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT04380545

Phase1, Phase2, Recruiting

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

for
Melanoma Stage III, Melanoma Stage IV
Location: La Jolla CA, San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT04598009

Phase2, Recruiting

Implantable Microdevice In Primary Brain Tumors

for
Grade II Glioma, Grade III Glioma, Grade IV Glioma, Astrocytoma,
Location: Boston MA
Sponsor: Oliver Jonas

Sex: All

Age: 18+

Code: NCT04135807

Early_phase1, Recruiting

Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

for
Plasma Cell Myeloma
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT05208307

Phase2, Recruiting

Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies

for
Monoclonal Gammopathy of Undetermined Significance,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05136807

Recruiting

Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization

for
Plasma Cell Myeloma
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT04211259

Early_phase1, Recruiting

Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer

for
Stage III Prostate Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Male

Age: 18+

Code: NCT04725903

Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for
Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8,
Location: Saint John, Bath ME, Portland ME, Scarborough ME,
Sponsor: NRG Oncology

Sex: Male

Age: 18+

Code: NCT05946213

Phase3, Recruiting

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

for
Heart Failure NYHA Class III, Heart Failure
Location: Naperville IL
Sponsor: Endotronix, Inc.

Sex: All

Age: 18+

Code: NCT06783335

Recruiting