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Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

for
Metastatic Colorectal Adenocarcinoma,
Location: Gainesville FL, Nashville TN, Shiloh IL, St Louis MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06696768

Phase1, Recruiting

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for
Smoldering Plasma Cell Myeloma
Location: York Village ME, Boston MA, Westerly RI, Waterford CT,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT03937635

Phase3, Recruiting

Optimizing HFrEF Patients Using BaroStim and CardioMems

for
Heart Failure NYHA Class III
Location: Riverhead NY
Sponsor: Northwell Health

Sex: All

Age: 18 - 70+

Code: NCT07399587

Phase2, Phase3, Recruiting
New

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

for
Demyelinating Disorders, MCI, Alzheimer's Disease (AD),
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18 - 70+

Code: NCT06999434

Phase1, Recruiting
New

A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy

for
Multiple Sclerosis
Location: Atlanta GA, Cordova TN
Sponsor: Genentech, Inc.

Sex: All

Age: 18 - 65

Code: NCT07609719

Recruiting

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PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

for
Multiple Sclerosis, Alzheimer's Disease
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18 - 70+

Code: NCT02649985

Phase1, Phase2, Recruiting

A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis

for
Multiple Sclerosis
Location: East Hanover NJ
Sponsor: Kessler Foundation

Sex: All

Age: 18 - 70

Code: NCT06197685

Recruiting

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

for
Multiple Sclerosis, Relapsing-Remitting
Location: Tampa FL, Louisville KY, Chicago IL, Milwaukee WI,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 10 - 17

Code: NCT06408259

Phase3, Recruiting

Transcutaneous Spinal Cord Stimulation Home Study

for
Spinal Cord Injuries,
Location: Vancouver
Sponsor: Michael Berger

Sex: All

Age: 19 - 70

Code: NCT06838637

Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

for
Autonomic Failure, Pure Autonomic Failure, Parkinson Disease,
Location: Nashville TN
Sponsor: Daniel Claassen

Sex: All

Age: 18+

Code: NCT04246437

Phase1, Recruiting

An Individualized-health eLibrary App for People With Multiple Sclerosis

for
Multiple Sclerosis
Location: Champaign IL
Sponsor: University of Illinois at Urbana-Champaign

Sex: All

Age: 18+

Code: NCT05124600

Recruiting

A Study of NeuroVax™, a Therapeutic TCR Peptide Vaccine for SPMS of Multiple Sclerosis

for
Secondary Progress Multiple Sclerosis, Multiple Sclerosis
Location: San Diego CA
Sponsor: Immune Response BioPharma, Inc.

Sex: All

Age: 18 - 50

Code: NCT02057159

Phase2, Phase3, Recruiting

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

for
Multiple System Atrophy
Location: Boston MA, New York NY, Pittsburgh PA, Tampa FL,
Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All

Age: 30 - 70+

Code: NCT06568237

Phase2, Recruiting

Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals

for
Stroke, Multiple Sclerosis
Location: Houston TX
Sponsor: Texas Woman's University

Sex: All

Age: 21 - 70+

Code: NCT04503187

Recruiting

Measurement and Training of Dual-Task of Gait in Persons With Multiple Sclerosis

for
Multiple Sclerosis, Gait Disorders, Neurologic,
Location: Houston TX
Sponsor: Texas Woman's University

Sex: All

Age: 18 - 65

Code: NCT03536299

Recruiting

Post-Authorization Safety Study for Assessment of Pregnancy Outcomes in Patients Treated With Mayzent

for
Multiple Sclerosis
Location: La Jolla CA
Sponsor: Novartis Pharmaceuticals

Sex: Female

Age: 0+

Code: NCT04933552

Recruiting

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

for
Central Nervous System Disease, Multiple Sclerosis
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 0 - 70+

Code: NCT00794352

Recruiting

A Palliative Care Model Impact on Knowledge and Attitudes

for
Multiple Sclerosis, MS
Location: New York NY
Sponsor: Hunter College of City University of New York

Sex: All

Age: 18 - 65

Code: NCT06860932

Recruiting

Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training

for
Complete Spinal Cord Injury, Incomplete Spinal Cord Injury,
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT03057652

Recruiting

Solriamfetol for the Treatment of Multiple Sclerosis Fatigue

for
Multiple Sclerosis, Multiple Sclerosis Fatigue
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18 - 60

Code: NCT06170970

Phase2, Recruiting