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Active & Responsive

Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families

for
Racially/Ethnically Diverse Families From Urban Settings
Location: Athens GA, Minneapolis MN
Sponsor: University of Colorado, Denver

Sex: All

Age: 8 - 18

Code: NCT05744973

Recruiting
Active & Responsive

Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.

for
Dentin Hypersensitivity, Erosive Tooth Wear
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07195357

Recruiting
Active & Responsive

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

for
Otitis Media With Effusion, Acute Otitis Media, Otitis Media
Location: New York NY, New Brunswick NJ, Cherry Hill NJ,
Sponsor: Smith & Nephew, Inc.

Sex: All

Age: 0 - 17

Code: NCT05915078

Recruiting
Active & Responsive

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

for
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
Location: Worcester MA, Charlottesville VA, Ann Arbor MI,
Sponsor: University of Massachusetts, Worcester

Sex: All

Age: 18 - 70+

Code: NCT06855329

Recruiting
Active & Responsive

Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease

for
Parkinson Disease, Depression, PARKINSON DISEASE (Disorder)
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 40 - 70+

Code: NCT05568498

Phase2, Recruiting

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Active & Responsive

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

for
Cancer, Breast Cancer, Lung Cancer, Colon Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03702309

Recruiting
Active & Responsive

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for
Autoimmune Disease, Crohn Disease, Dermatomyositis,
Location: Boston MA, New Haven CT, Mineola NY, New York NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03816345

Phase1, Recruiting
Active & Responsive

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

for
Chronic Pain, Acute Pain, Post Operative Pain,
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT05754190

Recruiting
Active & Responsive

RASopathy Biorepository

for
RAS Mutation, Neurofibromatosis 1, Noonan Syndrome,
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT04395495

Recruiting
Active & Responsive

Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)

for
Back Pain Lower Back, Neck Pain, Radiculopathy Multiple Sites,
Location: Thornhill
Sponsor: Igor Wilderman. MD

Sex: All

Age: 18+

Code: NCT07762170

Recruiting
Active & Responsive

PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

for
Coronary Artery Disease Risk Factors Multiple,
Location: New York NY, Durham NC, Hiram GA, Birmingham AL,
Sponsor: Duke University

Sex: All

Age: 30 - 60

Code: NCT07232069

Phase3, Recruiting
Active & Responsive

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

for
Primary Hyperparathyroidism, Parathyroid Cancer,
Location: Bethesda MD
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 18 - 70+

Code: NCT07444723

Phase2, Phase3, Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Boston MA, Waterford CT, Guilford CT, New Haven CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Westerly RI, Waterford CT, Guilford CT, Glastonbury CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase2, Phase3, Recruiting
Active & Responsive

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Location: Rockport ME, Belfast ME, Damariscotta ME, Augusta ME,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07018869

Phase3, Recruiting
Active & Responsive

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

for
Capsular Contracture Associated With Breast Implant,
Location: West Long Branch NJ, New York NY, Miami FL,
Sponsor: C. R. Bard

Sex: Female

Age: 22 - 70

Code: NCT05945329

Recruiting
Active & ResponsiveNew

CREO - Microwave Ablation Feasibility Study

for
Pancreatic Cancer,
Location: Gilbert AZ
Sponsor: Banner Health

Sex: All

Age: 18+

Code: NCT07817147

Recruiting
Active & ResponsiveNew

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma

for
Locally Advanced Ampulla of Vater Carcinoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07780838

Phase2, Recruiting
Active & Responsive

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

for
Human Papillomavirus Type 16,
Location: Baltimore MD, Birmingham AL
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female

Age: 19+

Code: NCT04131413

Phase1, Recruiting
Active & Responsive

Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis

for
Metastatic Penile Squamous Cell Carcinoma,
Location: Jacksonville FL, Rochester MN, Phoenix AZ
Sponsor: Mayo Clinic

Sex: Male

Age: 18+

Code: NCT06104618

Phase2, Recruiting