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Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

for
Primary Sclerosing Cholangitis, Inflammatory Bowel Diseases
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18 - 70+

Code: NCT05912387

Early_phase1, Recruiting

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

for
Chronic Daily Headache
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 70+

Code: NCT05306899

Phase3, Recruiting

MyPEEPS Mobile Plus: A Multi-Level HIV Prevention Intervention for Young MSM

for
HIV/AIDS
Location: New York NY
Sponsor: Columbia University

Sex: Male

Age: 16 - 25

Code: NCT06741618

Recruiting

Multi-center Evaluation of the Clinical Utility of ESD in the Western Population

for
Endoscopic Submucosal Dissection
Location: Boston MA, Gainesville FL, Houston TX
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT02989818

Recruiting

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

for
Chronic Low-back Pain
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT04730700

Recruiting

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Multi-disciplinary Care for Brain Metastases

for
Brain Metastases, Adult
Location: Burlington VT
Sponsor: University of Vermont Medical Center

Sex: All

Age: 18+

Code: NCT06280300

Recruiting

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury

for
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level,
Location: Cleveland OH
Sponsor: Anne Bryden

Sex: All

Age: 17+

Code: NCT02329652

Recruiting

Multi-Omics for Maternal Health After Preeclampsia

for
Pre-Eclampsia, Pregnancy Induced Hypertension
Location: San Diego CA
Sponsor: University of California, San Diego

Sex: Female

Age: 18 - 50

Code: NCT06340152

Recruiting

Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry

for
Ischemic Stroke
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT02923752

Recruiting

The McMaster Multi-Regional COVID-19 Hospital Case Registry

for
Coronavirus Infection, Coronavirus, SARS-CoV-2 Infection,
Location: St. Catharines, Hamilton, Kitchener
Sponsor: McMaster University

Sex: All

Age: 18+

Code: NCT04508959

Recruiting

Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility Study

for
HER2-positive Breast Cancer, LMD
Location: Ottawa, Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06016387

Phase2, Recruiting

The Ontario Multi-Regional Hospital COVID-19 Registry (COREG)- Recovery Trajectory Sub-study

for
COVID-19 Pneumonia, Sars-CoV-2 Infection
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: All

Age: 18+

Code: NCT04868864

Recruiting

Multi-Center Single Arm Trial to Determine The Effectiveness of Warfarin Therapy Duration For Heparin-Induced Thrombocytopenia (HIT)

for
Heparin-induced Thrombocytopenia
Location: Huntington WV
Sponsor: Marshall University

Sex: All

Age: 18 - 70+

Code: NCT03147638

Phase3, Recruiting

Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia, CLL, Untreated, Front-line,
Location: Boston MA, New Hyde Park NY, Houston TX, La Jolla CA
Sponsor: Chronic Lymphocytic Leukemia Research Consortium

Sex: All

Age: 0+

Code: NCT00628238

Phase2, Recruiting

Knotless Implants As an Alternative for Capsular Closure in Primary Hip Arthroscopy: a Prospective, Multi-Center Study

for
Femoro Acetabular Impingement
Location: Des Plaines IL
Sponsor: American Hip Institute

Sex: All

Age: 18 - 60

Code: NCT06500364

Recruiting

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

for
Malignant Peripheral Nerve Sheath Tumors
Location: Baltimore MD, Toronto, St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 0+

Code: NCT03141021

Recruiting

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for
Pediatric Patients Treated With Radiation Therapy
Location: Boston MA, New York NY, Somerset NJ, Philadelphia PA,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 0 - 21

Code: NCT01696721

Recruiting

Fibrin for Chronic Multi-level Discogenic Low Back Pain

for
Low Back Pain, Disc Disease, Disc Degeneration, Radiculopathy,
Location: Tyler TX
Sponsor: Pauza, Kevin, MD

Sex: All

Age: 18 - 70+

Code: NCT04621799

Phase2, Phase3, Recruiting

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

for
Crohn Disease
Location: Seattle WA
Sponsor: Seattle Children's Hospital

Sex: All

Age: 8 - 21

Code: NCT06216899

Recruiting

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

for
Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance,
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 35 - 65

Code: NCT05165706

Recruiting