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Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies

for
Hematologic Malignancy, Large B-cell Lymphoma,
Location: Los Angeles CA
Sponsor: Joshua Sasine, MD, PhD

Sex: All

Age: 18 - 70+

Code: NCT05887167

Phase1, Recruiting

Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource

for
Plasma Cell Dyscrasias,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT01408225

Recruiting

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

for
Hematologic Malignancy, Blood Cancer, Lymphoma, Leukemia,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05646576

Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Weymouth MA, Boston MA, Brighton MA, Methuen MA,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT02269592

Recruiting

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The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase2, Recruiting

A Cognitive Training Intervention for Improving Cognitive and Neurological Outcomes in Patients Undergoing Treatment for Relapsed or Refractory Multiple Myeloma or B-cell Non-Hodgkin Lymphoma

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07609030

Recruiting

Survivors Uniting for Remote Guided Exercise

for
Cancer,
Location: Fort Collins CO
Sponsor: Colorado State University

Sex: All

Age: 18+

Code: NCT07290309

Recruiting

Transgene Assay Testing Service of Tumor Samples From Patients Who Received a Bristol-Myers Squibb Manufactured Gene Modified Cell Therapy and Have a Qualifying Second Primary Malignancy

for
Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukaemia,
Location: Dallas TX, Salt Lake City UT
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 0+

Code: NCT06357754

Recruiting

Two Step Haplo With Radiation Conditioning

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Philadephia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05031897

Phase2, Recruiting

Pre-malignant States to Hematologic Malignancies in Firefighters

for
Clonal Hematopoiesis of Indeterminate Potential,
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 40 - 49

Code: NCT06870760

Recruiting

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

for
Cancer, Cancer Survivors, Gastrointestinal Cancers,
Location: Detroit MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT06908629

Recruiting

Integrated Cancer Repository for Cancer Research

for
Pancreatic Cancer, Thyroid Cancer, Lung Cancer,
Location: Manchester CT, Holyoke MA, Glens Falls NY, Utica NY,
Sponsor: University of Nebraska

Sex: All

Age: 19 - 70+

Code: NCT02012699

Recruiting

Study of CAR-T Therapy in Older Patients

for
Lymphoma, Refractory B-Cell Lymphoma, Lymphoma, B-Cell,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT04300998

Recruiting

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

for
B-Cell Lymphoma, Myelodysplastic Syndromes (MDS),
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12 - 70+

Code: NCT05092451

Phase1, Phase2, Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for
Hematologic Malignancies, Inherited Disorders of Metabolism,
Location: Boston MA, New Haven CT, Stony Brook NY, Lake Sucess NY,
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 0+

Code: NCT01351545

Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

for
Endocrine Tumors, Non-Small Cell Lung Cancer, Ovarian Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03412877

Phase2, Recruiting

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

for
Haematological Malignancy, Acute Myeloid Leukemia,
Location: Philadelphia PA, Bethesda MD, Atlanta GA,
Sponsor: CellCentric Ltd.

Sex: All

Age: 18+

Code: NCT04068597

Phase1, Phase2, Recruiting

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

for
Hypogammaglobulinemia, Bacterial Infections,
Location: Greenville NC, Bethesda MD, Morrisville NC,
Sponsor: Grifols Therapeutics LLC

Sex: All

Age: 18+

Code: NCT05645107

Phase3, Recruiting

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

for
Malignant Neoplasm of Bone and Articular Cartilage,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12 - 50

Code: NCT03093909

Phase1, Recruiting