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Interprofessional Pharmacogenomics (IPGx) Registry and Repository

for
Diabetes, Cholesterol, Cancer, Blood Pressure Disorders,
Location: Bryan TX
Sponsor: Texas A&M University

Sex: All

Age: 18+

Code: NCT06726590

Recruiting

Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

for
Diffuse Large B-Cell Lymphoma, High-grade B-cell Lymphoma,
Location: Los Angeles CA, Sacramento CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18 - 70

Code: NCT05256641

Phase1, Phase2, Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

for
High Grade Glioma, Meningioma, Embryonal Tumor, Medulloblastoma,
Location: Columbus OH, Cincinnati OH
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 4 - 39

Code: NCT05278208

Phase1, Phase2, Recruiting

Natural History of Depression, Bipolar Disorder and Suicide Risk

for
Behavioral Symptoms, Suicide, Self-Injurious Behavior,
Location: Bethesda MD
Sponsor: National Institute of Mental Health (NIMH)

Sex: All

Age: 18 - 70+

Code: NCT06462196

Recruiting

A Study of NX-1607 in Adults With Advanced Malignancies

for
Ovarian Cancer, Epithelial, Gastric Cancer,
Location: Charlottesville VA, Chapel Hill NC, Chicago IL,
Sponsor: Nurix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05107674

Phase1, Recruiting

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Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

for
Non Hodgkin Lymphoma,
Location: Boston MA, New Haven CT, Durham NC, Chicago IL,
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18+

Code: NCT06116110

Recruiting

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

for
Spinal Cord Injuries, Spinal Cord Diseases,
Location: West Orange NJ
Sponsor: Kessler Foundation

Sex: All

Age: 18 - 70+

Code: NCT05731986

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04771520

Phase2, Recruiting

Cancer Genetic Testing in Ethnic Populations

for
Breast Carcinoma, Carcinoma of Unknown Primary,
Location: Jacksonville FL, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04475640

Recruiting

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

for
Breast Carcinoma, Esophageal Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00991094

Recruiting

Lymphatic Anomalies Registry for the Assessment of Outcome Data

for
Lymphatic Malformation, Generalized Lymphatic Anomaly (GLA),
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT02399527

Recruiting

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for
Diffuse Intrinsic Pontine Glioma, DIPG, Brain Tumor, CNS Tumor,
Location: Seattle WA
Sponsor: BrainChild Bio, Inc

Sex: All

Age: 1 - 26

Code: NCT07680439

Phase2, Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

for
Recurrent Glioblastoma,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT07416188

Phase1, Phase2, Recruiting

Exploring the Feasibility of Cerebrospinal Fluid (CSF) and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and Primary Central Nervous System (CNS) Tumours: A Pilot Study

for
Solid Tumor Malignancies, Brain Metastasases,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07476781

Recruiting

Q702 for the Treatment of Patients With Hematologic Malignancies

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06712810

Phase1, Recruiting

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

for
Traumatic Brain Injury, Stroke, Brain Disease,
Location: Pittsburgh PA
Sponsor: Jorge Gonzalez-Martinez

Sex: All

Age: 18 - 70+

Code: NCT07056348

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for
Coronavirus Infection (COVID-19),
Location: Montreal, Durham NC, Cincinnati OH, Austin TX,
Sponsor: Duke University

Sex: All

Age: 0 - 20

Code: NCT04278404

Recruiting

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for
Relapsed Hematologic Malignancy,
Location: Boston MA, New York NY, Durham NC, Buffalo NY,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT03328078

Phase1, Phase2, Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

for
Neoplasms, Brain, Glioblastoma Multiforme,
Location: Birmingham AL, St Louis MO, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 3 - 22

Code: NCT03911388

Phase1, Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma,
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 25

Code: NCT03959085

Phase3, Recruiting