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A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain

for
Non Small Cell Lung Cancer Metastatic
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06741085

Phase2, Recruiting

Analysis of RATS, VATS and Open Lung Resections After Neoadjuvant Chemo-immunotherapy in Patients Performed in Five Referred Centers

for
Non-Small Cell Lung Cancer
Location: New York NY, Miami FL, Morgantown WV
Sponsor: Scientific Institute San Raffaele

Sex: All

Age: 18+

Code: NCT06626243

Recruiting

Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features

for
Non-small Cell Lung Cancer Stage III
Location: Washington D.C. DC, Charlottesville VA, St Louis MO
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT06449313

Phase2, Recruiting

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

for
Non-Small Cell Lung Cancer, Small Cell Lung Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT02146170

Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for
Advanced Solid Tumor, Advanced Malignant Neoplasm,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: PMV Pharmaceuticals, Inc

Sex: All

Age: 12+

Code: NCT04585750

Phase1, Phase2, Recruiting

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Tumor Treating Fields for Locally Advanced NSCLC

for
Non Small Cell Lung Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 22+

Code: NCT06124118

Phase1, Recruiting

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: Columbus OH, Grand Rapids MI, Houston TX,
Sponsor: Tanabe Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT06943521

Phase1, Phase2, Recruiting

Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer

for
Advanced Non Small Cell Lung Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05777603

Phase1, Recruiting

Genomic Investigation of Unusual Responders

for
Cancer, Breast Cancer, Non-small Cell Lung Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03740503

Recruiting

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

for
Advanced Non-Small Cell Lung Cancer,
Location: South Weymouth MA, Boston MA, Brighton MA,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04613596

Phase2, Phase3, Recruiting

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

for
Invasive Ductal Breast Carcinoma,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05837767

Recruiting

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

for
Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung,
Location: Fairhaven MA, Portland ME, Scarborough ME,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06758401

Phase3, Recruiting

Phase 2 Study of Fingolimod in Lung Cancers

for
Non Small Cell Lung Cancer, Small-cell Lung Cancer
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT06424067

Phase2, Recruiting

A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05657873

Phase2, Recruiting

Comparing Hypo-fractionated Intensity- Modulated Radiation Therapy to Standard- Fractionated IMRT Along With Chemotherapy and Immunotherapy for Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer Stage
Location: Lee's Summit MO, Kansas City KS, Kansas City MO,
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT04992780

Phase2, Recruiting

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Fairfax VA, Irving TX, Austin TX, San Antonio TX
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT06090266

Phase1, Phase2, Recruiting
New

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07322341

Phase2, Recruiting
New

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

for
Early Stage Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07718672

Phase2, Recruiting

PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

for
NSCLC Stage II, NSCLC, Stage III
Location: Galveston TX, Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06945484

Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for
Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
Location: Philadelphia PA, Fairfax VA, Dallas TX,
Sponsor: Lantern Pharma Inc.

Sex: All

Age: 18+

Code: NCT05456256

Phase2, Recruiting