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ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer

for
Pancreatic Cancer
Location: Los Angeles CA
Sponsor: Anova Innovation Limited

Sex: All

Age: 18+

Code: NCT07444541

Phase1, Phase2, Recruiting

EUS Procedures Using RIVOS™ EUS Access Device

for
Pancreatic Fluid Collections, Biliary Obstruction,
Location: Orlando FL
Sponsor: Orlando Health, Inc.

Sex: All

Age: 18+

Code: NCT07696572

Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Pittsburgh PA, Gainesville FL, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05372614

Phase1, Recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

for
Gastric Cancer, Gastric Adenocarcinoma,
Location: Fairfax VA
Sponsor: BigHat Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07529808

Phase1, Phase2, Recruiting

To Evaluate the Preliminary Efficacy of Our Digitally Enhanced CHW-led Intervention in Newly Diagnosed PDAC

for
Pancreatic Cancer, Adult
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 1+

Code: NCT07591571

Recruiting

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Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

for
Pancreatic Cancer
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06141031

Phase1, Recruiting

Axelopran for Advanced Cancer in Patients Receiving Opioids

for
Breast Cancer, Lung Cancer, Pancreas Cancer, Prostate Cancer
Location: Saint Paul MN, Saint Louis Park MN
Sponsor: HealthPartners Institute

Sex: All

Age: 18+

Code: NCT07354919

Phase2, Recruiting

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

for
Pancreatic Adenocarcinoma, Cancer of the Pancreas,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07126158

Phase2, Recruiting

PhIbRandomGemcitabine(G)w/or w/Out Pitavastatin(P)MainTx UnresecPancreaticAdenocarcinoma(uPDAC)

for
Pancreatic Cancer, Pancreatic Cancer Metastatic
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07549958

Phase1, Recruiting

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Boston MA, New York NY, Montreal, Baltimore MD,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07491445

Phase3, Recruiting

Prehab for Pancreatic Cancer Surgery

for
Pancreatic Cancer, Adult, Prehabilitation
Location: Worester MA
Sponsor: University of Massachusetts, Worcester

Sex: All

Age: 18+

Code: NCT07478185

Recruiting

Feasibility Study of Suizenji, in Patients With Unresectable Pancreatic Ductal Adenocarcinoma (SUNRISE-II)

for
Pancreatic Cancer
Location: San Francisco CA
Sponsor: SONIRE Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07033689

Early_phase1, Recruiting

PANCREATIC DISEASE COHORT A Registry and Biospecimen Bank to Better Understand Pancreatic Disease

for
Pancreatic Cancer
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18 - 70+

Code: NCT01102556

Recruiting

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Pancreatic Cancer

for
Pancreatic Cancer
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT07254091

Early_phase1, Recruiting

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

for
Pancreatic Cancer, Metastatic Pancreatic Cancer,
Location: Providence RI, Hartford CT, Lebanon NH, Commack NY,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07409272

Phase3, Recruiting

Distance-Based Exercise to Preserve Function and Prevent Disability

for
Localized Malignant Solid Neoplasm, Anal Cancer,
Location: Boston MA, Indiana PA, Kernersville NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07059884

Recruiting

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

for
Foregut Adenocarcinoma, Esophageal Adenocarcinoma,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18 - 70+

Code: NCT07282912

Phase2, Recruiting

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

for
Locally Advanced Pancreatic Ductal Adenocarcinoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07089940

Early_phase1, Recruiting

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Stamford CT, Millville DE, Lewes DE, Rehoboth Beach DE,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06998940

Phase3, Recruiting

A Study of Narmafotinib Given in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer

for
Pancreatic Cancer Metastatic
Location: Cleveland OH
Sponsor: Amplia Therapeutics Limited

Sex: All

Age: 18+

Code: NCT07026279

Phase1, Phase2, Recruiting