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A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC

for
Metastatic Head and Neck Squamous Cell Carcinoma,
Location: Tyler TX
Sponsor: Bicara Therapeutics

Sex: All

Age: 18+

Code: NCT07807163

Phase2, Recruiting
New

Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients

for
Head and Neck Disorder, Head and Neck Cancer
Location: Pittsburgh PA
Sponsor: Matthew Spector

Sex: All

Age: 18+

Code: NCT07631650

Phase2, Recruiting

New MRI Biomarkers in Head and Neck Cancers

for
Head and Neck Cancer, Thyroid Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT03483337

Recruiting

Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC

for
Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC),
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05414032

Phase2, Recruiting

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

for
Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05726370

Phase2, Recruiting

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Circulating Tumor DNA Exposure in Peripheral Blood

for
Colorectal Cancer, Pancreatic Adenocarcinoma, Gastric Cancer,
Location: Orlando FL, Celebration FL, Centerville OH, Dayton OH
Sponsor: Quantgene Inc.

Sex: All

Age: 18+

Code: NCT03517332

Recruiting

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, New York NY, Ottawa, Washington D.C. DC,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06586515

Phase1, Recruiting

5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC

for
Squamous Cell Carcinoma of Head and Neck
Location: New Haven CT
Sponsor: Barbara Burtness

Sex: All

Age: 18+

Code: NCT05317000

Phase2, Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for
Pheochromocytoma/Paraganglioma, Pancreatic Neuroendocrine Tumor,
Location: Boston MA, Baltimore MD, Bethesda MD, Toronto,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 12+

Code: NCT04924075

Phase2, Recruiting

HN-QUEST: A Study of Head and Neck Imaging Biomarkers

for
Head and Neck Squamous Cell Carcinoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05919290

Recruiting

Chemoprevention With Tamoxifen in Pre-Invasive Pancreas Mucinous Cystic Neoplasms Not Undergoing Immediate Resection

for
Pancreatic Cyst, Pancreatic Mucinous Cystic Neoplasm
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT06320990

Phase1, Recruiting

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

for
Head and Neck Cancer, Lung Cancer, Lip Cancer, Lip Neoplasms,
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT00568490

Recruiting

Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma

for
Locally Advanced Unresectable Pancreatic Adenocarcinoma
Location: Duarte CA, Irvine CA
Sponsor: Impact Biotech Ltd

Sex: All

Age: 18+

Code: NCT05919238

Phase1, Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: Fairhaven MA, Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

for
Head and Neck Cancer, Lung Cancer, Gastrointestinal Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05995821

Recruiting

Microbiome in Head and Neck Squamous Cell Carcinoma

for
Head and Neck Cancer, Lip Cancer, Oral Cancer, Pharynx Cancer
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT05837221

Recruiting

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Livingston NJ, New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT05296421

Recruiting

The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

for
Head and Neck Cancer, Survivorship, Caregiver Burden,
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05811936

Recruiting

A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Ductal Adenocarcinoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05851924

Phase2, Recruiting

Use Of Indocyanine Green In Pancreas Surgery

for
Pancreatic Carcinoma
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06084013

Recruiting