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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for
Head and Neck Squamous Cell Carcinoma
Location: St. John's, Hackensack NJ, Philadelphia PA, Norfolk VA,
Sponsor: Merus B.V.

Sex: All

Age: 18+

Code: NCT06525220

Phase3, Recruiting

Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

for
Advanced Head and Neck Cancer
Location: Quebec, Montreal, Ottawa, Toronto, Winnipeg, Edmonton,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06641791

Phase3, Recruiting

Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07199764

Phase2, Recruiting

Prehabilitation Protocol for Head and Neck Cancer Patients

for
Head and Neck Cancer
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18 - 70+

Code: NCT07318220

Recruiting

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

for
Head and Neck Carcinoma of Unknown Primary,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04754321

Phase1, Recruiting

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A Study Comparing Two Immunotherapy Options for Human Papillomavirus Positive HPV-Positive Head and Neck Cancer After Treatment

for
Head and Neck Cancer
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07179315

Phase2, Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma (PDAC), G12D Mutated KRAS
Location: Boston MA, New York NY, East Brunswick NJ, Baltimore MD,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07644559

Phase2, Recruiting

The Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer

for
Head and Neck Cancers
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 18+

Code: NCT07622914

Recruiting

MyCap Mobile Application for Tracking Time Burden of Treatment for Patients With Pancreatic Cancer

for
Pancreatic Adenocarcinoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07619391

Recruiting

Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cystic Neoplasms

for
Pancreatic Cystic Neoplasm
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07529483

Phase2, Recruiting

Skin Color Matching in Head and Neck Reconstructive Surgery

for
Head and Neck Cancer, Head and Neck Trauma
Location: Guilford CT, New Haven CT, Milford CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07431099

Recruiting

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT05420948

Phase2, Recruiting

Nutrition Intervention for Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma (PDAC),
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 18+

Code: NCT07554560

Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

for
Advanced Biliary Tract Carcinoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07405086

Recruiting

A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC)

for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07408063

Phase2, Recruiting

5-Fluorouracil Response and Optimization STudy (The FROST Trial)

for
Squamous Cell Carcinoma of Head and Neck,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07419464

Phase2, Recruiting

Window of Opportunity in Preserving Laryngeal Function Trial

for
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M),
Location: Pittsburgh PA
Sponsor: Matthew Spector

Sex: All

Age: 18+

Code: NCT07423078

Phase2, Recruiting

Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer

for
Head and Neck Cancer, HPV
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07065630

Phase2, Recruiting

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for
Head and Neck Squamous Cell Carcinoma (HNSCC)
Location: Willow Grove PA, Richmond VA, Fairfax VA, Rochester NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06769698

Phase2, Recruiting

Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO Trial

for
Cancer-Associated Anorexia,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06995508

Phase2, Recruiting