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New

Study of NXP900 With Lorlatinib in ALK+ Lung Cancer

for
ALK Positive, ALK Positive Non-small Cell Lung Cancer, NSCLC,
Location: Fairfax VA
Sponsor: Nuvectis Pharma, Inc.

Sex: All

Age: 0+

Code: NCT07784959

Phase1, Recruiting
New

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07322341

Phase2, Recruiting
New

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

for
Early Stage Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07718672

Phase2, Recruiting
New

Sacituzumab Tirumotecan +/- Pembrolizumab in I/O Exposed Metastatic or Recurrent Ovarian Clear Cell Cancer

for
Ovarian Clear Cell Carcinoma, Metastatic Ovarian Cancer,
Location: Boston MA
Sponsor: Tufts Medical Center

Sex: Female

Age: 18+

Code: NCT07718854

Phase2, Recruiting
New

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

for
Small Cell Lung Cancer Extensive Stage, Small-cell Lung Cancer,
Location: East Brunswick NJ, Fairfax VA, Glendale CA,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT07625644

Phase3, Recruiting

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New

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

for
Selected Advanced Solid Tumors, Colorectal Cancer (CRC),
Location: Glen Burnie MD
Sponsor: SK Life Science, Inc.

Sex: All

Age: 18+

Code: NCT07812805

Phase1, Recruiting
New

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

for
Clear Cell Renal Cell Carcinoma,
Location: New Haven CT
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07516366

Phase2, Recruiting
New

A Study of Armored CAR T Cells in People With Cancer

for
Neuroendocrine Cancer, Small Cell Lung Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07783477

Phase1, Recruiting
New

Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

for
Non Small Cell Lung Cancer, Metastatic Lung Cancer
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT06622174

Phase1, Recruiting
New

Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC)

for
Small Cell Lung Cancer
Location: Orlando FL, Grand Rapids MI, Omaha NE
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07778316

Phase3, Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for
Cervical Cancer,
Location: Hackensack NJ, Montreal, Hamilton, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT04895709

Phase1, Phase2, Recruiting

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

for
Squamous Non-small-cell Lung Cancer,
Location: New Haven CT, Hackensack NJ, Fairfax VA, Louisville KY,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT06747585

Phase1, Phase2, Recruiting

Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)

for
Non Small Cell Lung Cancer
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT06305715

Phase2, Recruiting

A Study of VET3-TGI in Patients With Solid Tumors

for
Solid Tumor, Adult, Microsatellite Stable Colorectal Cancer,
Location: Miami FL, Pittsburgh PA, Indianapolis IN, Houston TX,
Sponsor: KaliVir Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06444815

Phase1, Recruiting

Confocal Laser Endomicroscopy VERification

for
Lung Cancer, Lung Neoplasm Malignant,
Location: New York NY
Sponsor: Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Sex: All

Age: 18+

Code: NCT06079970

Recruiting

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

for
Small Cell Lung Cancer
Location: Boston MA, Hackensack NJ, Miami FL, Buffalo NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06780137

Phase1, Phase2, Recruiting

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

for
Small-cell Lung Cancer, Extensive-stage Small-cell Lung Cancer,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT05068232

Phase2, Recruiting

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

for
Extensive-stage Small-cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06807632

Phase1, Recruiting

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

for
Non-small Cell Lung Cancer (NSCLC)
Location: Nashville TN, Houston TX
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT06567015

Phase1, Phase2, Recruiting

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

for
Advanced Solid Tumor, Non Small Cell Lung Cancer,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Synthekine

Sex: All

Age: 18+

Code: NCT05098132

Phase1, Phase2, Recruiting