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A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: New York NY, Fairfax VA, Toronto
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07227025

Phase1, Phase2, Recruiting

The CARDIOPROTECT Trial

for
Diffuse Large B-cell Lymphoma (DLBCL), Cardiotoxicity, Lymphoma
Location: Boston MA
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 18+

Code: NCT07654426

Phase2, Recruiting

Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation

for
Hematopoietic Cell Transplant, Hematologic Malignancy
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06676852

Recruiting

Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07365306

Phase2, Recruiting

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

for
Carcinoma, Renal Cell
Location: New York NY, Ottawa, Marietta GA, Germantown TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07489495

Phase3, Recruiting

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A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC

for
Carcinoma, Non-Small-Cell Lung
Location: Toronto, Portland OR, Irvine CA, Duarte CA
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07586202

Phase2, Recruiting

Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

for
Recurrent T-Cell Non-Hodgkin Lymphoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07225985

Phase1, Phase2, Recruiting

A First-in-Human Study of CKD-703 in Advanced Solid Tumors and Non-Small Cell Lung Cancer

for
Advanced Solid Tumors, Non-Small Cell Lung Cancer
Location: Ohio City OH
Sponsor: Chong Kun Dang Pharmaceutical

Sex: All

Age: 19+

Code: NCT07439094

Phase1, Phase2, Recruiting

Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Study

for
Clear Cell Renal Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07187869

Phase1, Recruiting

Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial

for
Plasma Cell Leukemia
Location: Buffalo NY, Salt Lake City UT
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT07605416

Phase2, Recruiting

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

for
Chronic Lymphocytic Leukemia, CLL, Mantle Cell Lymphoma, MCL
Location: Boston MA, Tampa FL, Fort Wayne IN, St Louis MO,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06697184

Phase1, Phase2, Recruiting

Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified,
Location: Charlottesville VA, Winston-Salem NC, Tampa FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06015880

Phase1, Recruiting

eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation

for
Stem Cell Transplantation, Myelodysplastic Syndromes,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT07469592

Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms,
Location: New York NY, East Brunswick NJ, Norfolk VA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07218380

Phase3, Recruiting

The Spine Phenome Project

for
Low Back Pain, Neck Pain
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 18+

Code: NCT05776771

Recruiting

Two-photon Fluorescence Microscopy of Dermatologic Biopsies

for
Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma,
Location: Victor NY
Sponsor: University of Rochester

Sex: All

Age: 0+

Code: NCT07773688

Recruiting

Machine Learning Analysis of Two-photon Fluorescence Microscopy of Dermatologic Biopsies

for
Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma (Skin)
Location: Victor NY
Sponsor: University of Rochester

Sex: All

Age: 0+

Code: NCT07682831

Recruiting

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

for
Angioimmunoblastic T-cell Lymphoma,
Location: Boston MA, Saint Johnsbury VT, Lebanon NH, Commack NY,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT04803201

Phase2, Recruiting

Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia

for
Hairy Cell Leukemia, Recurrent Hairy Cell Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00412594

Phase2, Recruiting

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

for
Metastatic Chondrosarcoma, Locally Advanced Chondrosarcoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06176989

Phase2, Recruiting