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Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Weymouth MA, Boston MA, Brighton MA, Methuen MA,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT02269592

Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, Shirley NY, New Haven CT, Lebanon NH,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase2, Recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for
AIDS-Related Diffuse Large B-cell Lymphoma,
Location: The Bronx NY, New York NY, Philadelphia PA, Columbus OH,
Sponsor: AIDS Malignancy Consortium

Sex: All

Age: 18+

Code: NCT05077527

Phase1, Recruiting

NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

for
Hearing Loss, Head and Neck Neoplasms, Hearing Disorders,
Location: Bethesda MD
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)

Sex: All

Age: 3 - 70+

Code: NCT06303180

Recruiting

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for
Solid Tumors
Location: Boston MA, Lake Success NY, The Bronx NY, New York NY,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT07522073

Phase3, Recruiting

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A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)

for
Hairy Cell Leukemia
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06561360

Phase2, Recruiting

APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion

for
Fallopian Tube Carcinosarcoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: Female

Age: 18+

Code: NCT04919629

Phase2, Recruiting

MAGESTIC Trial: MiRNA in Detecting Active Germ Cell Tumors in Early Suspected and MetastaTIC Disease Trial

for
Malignant Testicular Germ Cell Tumor
Location: New Brunswick NJ, Toronto, Atlanta GA, Birmingham AL,
Sponsor: University of Southern California

Sex: Male

Age: 18+

Code: NCT06060873

Recruiting

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

for
Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma
Location: Washington D.C. DC, Fairfax VA, Plantation FL,
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All

Age: 18+

Code: NCT07407933

Phase1, Phase2, Recruiting

Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma

for
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06485076

Recruiting

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for
Relapsed or Refractory T Cell Lymphoma
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Ono Pharmaceutical Co. Ltd

Sex: All

Age: 18+

Code: NCT05079282

Phase1, Recruiting

Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study

for
Lung Non-Small Cell Carcinoma
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07339254

Recruiting

Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

for
Hodgkin Disease, CD30-Positive Diffuse Large B-Cell Lymphoma,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT05544968

Phase1, Recruiting

Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX, Dallas TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 6 - 29

Code: NCT04678427

Recruiting

Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

for
Graft-versus-Host Disease (GVHD), Hematologic Malignancies,
Location: Hershey PA
Sponsor: Milton S. Hershey Medical Center

Sex: All

Age: 18+

Code: NCT06926595

Phase2, Recruiting

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

for
Large B-cell Lymphoma
Location: Halifax, Boston MA, Quebec, New York NY, Hackensack NJ,
Sponsor: Allogene Therapeutics

Sex: All

Age: 18+

Code: NCT06500273

Phase2, Recruiting

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

for
Large B-Cell Lymphoma With IRF4 Rearrangement,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06834373

Phase2, Recruiting

Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients

for
Mantle Cell Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06263491

Phase2, Recruiting

Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Standard of Care Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Study

for
Stem Cell
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06004063

Recruiting

Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for
Lymphoma Diffuse Large B-cell, Leukemia and Lymphoma,
Location: Nashville TN
Sponsor: AvenCell Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07284433

Phase1, Phase2, Recruiting