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Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

for
Acute Leukemia, Acute Myeloid Leukemia,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 60

Code: NCT03314974

Phase2, Recruiting

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

for
Advanced Renal Cell Carcinoma (aRCC),
Location: Hershey PA, Washington D.C. DC, Chapel Hill NC,
Sponsor: Brian Rini

Sex: All

Age: 18+

Code: NCT07188896

Phase2, Recruiting

Registry to Collect Health Information About Desmoplastic Small Round Cell Tumor

for
Desmoplastic Small Round Cell Tumor
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT04690374

Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

for
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70+

Code: NCT01890486

Recruiting

Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma

for
Double-Expressor Lymphoma,
Location: San Diego CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT05600686

Phase2, Recruiting

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Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

for
Multiple Myeloma, Stem Cell Transplant Complications
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05706766

Recruiting

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

for
Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT05990465

Phase1, Recruiting

International Rare Histiocytic Disorders Registry (IRHDR)

for
Rare Histiocytic Disorders (RHDs),
Location: Boston MA, New York NY, Toronto, Pittsburgh PA,
Sponsor: The Hospital for Sick Children

Sex: All

Age: 0+

Code: NCT02285582

Recruiting

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

for
Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06227026

Phase1, Recruiting

Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

for
Hematopoietic and Lymphoid Cell Neoplasm, Immunocompromised
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT03425526

Phase1, Recruiting

Cemiplimab and Cetuximab Prior Salvage Surgery in Patients With Recurrent Oral Cavity and HPV-negative Oropharyngeal Squamous Cell Carcinoma

for
Locally Recurrent Oral Cavity Squamous Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06448026

Phase2, Recruiting

Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

for
Burkitt Lymphoma, Double-Expressor Lymphoma,
Location: Pittsburgh PA, Kansas City KS, Westwood KS, Fairway KS,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07069699

Phase1, Phase2, Recruiting

Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia

for
Head and Neck Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07278557

Phase2, Recruiting

Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study

for
B-Cell Non-Hodgkin Lymphoma, Multiple Myeloma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06052826

Phase2, Recruiting

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

for
Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma,
Location: Durham NC, Ann Arbor MI, Houston TX, Dallas TX,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05563766

Phase2, Recruiting

Molecular Epidemiology of Pediatric Germ Cell Tumors

for
Germ Cell Tumor, Germinoma, Teratoma, Embryonal Carcinoma,
Location: Minneapolis MN
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT05564026

Recruiting

Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer

for
Ovarian Clear Cell Adenocarcinoma,
Location: Buffalo NY, Houston TX
Sponsor: Roswell Park Cancer Institute

Sex: Female

Age: 18+

Code: NCT05231122

Phase2, Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma,
Location: Columbus OH, Sioux Falls SD, Orange CA, Eugene OR
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT01804686

Phase3, Recruiting

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

for
Peripheral T Cell Lymphoma, Relapsed Peripheral T-Cell Lymphoma,
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06508463

Phase1, Recruiting

Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation

for
Recurrent Renal Cell Carcinoma, Renal Cell Carcinoma
Location: Philadelphia PA
Sponsor: john eisenbrey

Sex: All

Age: 18+

Code: NCT05641935

Phase2, Recruiting