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Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

for
Recurrent Endometrial Carcinoma,
Location: Providence RI, Philadelphia PA, Cleveland OH,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05950464

Phase1, Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

for
Anal Carcinoma, Hematopoietic and Lymphoid Cell Neoplasm,
Location: New York NY, Baltimore MD, Washington D.C. DC, Miami FL,
Sponsor: AIDS Malignancy Consortium

Sex: All

Age: 18+

Code: NCT05663502

Recruiting

CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study

for
Multiple Myeloma, Multiple Myeloma Progression,
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 30+

Code: NCT06644625

Recruiting

Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma

for
Clear Cell Carcinoma, Phase 1, Growth Factor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07072234

Phase1, Recruiting

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

for
Leukemia, Hematopoetic Stem Cell Transplantation,
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 21 - 55

Code: NCT06643221

Early_phase1, Recruiting

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A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy)

for
T-cell Acute Lymphoblastic Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0 - 21

Code: NCT06561074

Phase2, Recruiting

Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial

for
Ewing Sarcoma, Round Cell Sarcoma With EWSR1-non-ETS Fusion
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 2+

Code: NCT07188532

Recruiting

Mosunetuzumab With Lenalidomide Augmentation as First-line Therapy for Follicular and Marginal Zone Lymphoma

for
Follicular Lymphoma, Marginal Zone Lymphoma, B-cell Lymphoma
Location: Providence RI, New Brunswick NJ
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT04792502

Phase2, Recruiting

Epcoritamab and Lenalidomide in Treating Patients With Refractory or Relapsed Immunodeficiency-Related Large B-Cell Lymphoma

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Chicago IL
Sponsor: Reem Karmali

Sex: All

Age: 18+

Code: NCT06723457

Phase2, Recruiting

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

for
Desmoplastic Small Round Cell Tumor, Osteosarcoma,
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12 - 39

Code: NCT04616560

Phase2, Recruiting

A Study of Cemiplimab and Fianlimab in People With Clear Cell Renal Cell Carcinoma

for
Renal Cell Carcinoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06699602

Phase2, Recruiting

Phase 2 Trial of Lisocabtagene Maraleucel for Minimal Residual Disease in Patients With Large B-cell Lymphoma

for
Large B-cell Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07316010

Phase2, Recruiting

A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer

for
HPV-Related Squamous Cell Carcinoma
Location: Hartford CT, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06563479

Phase3, Recruiting

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: New Haven CT, Mineola NY, New York NY, Chicago IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05272384

Phase1, Recruiting

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

for
Lung Non-Small Cell Carcinoma
Location: Stony Brook NY, Neptune City NJ, Red Bank NJ, Brick NJ,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07388524

Phase3, Recruiting

Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta

for
DLBCL - Diffuse Large B Cell Lymphoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05950802

Phase1, Recruiting

Study of Intralesional FLD-103 in Subjects With Basal Cell Carcinoma (BCC)

for
Nodular Basal Cell Carcinoma
Location: Bowling Green KY
Sponsor: Feldan Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT07670858

Phase1, Recruiting

Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma

for
Recurrent Adult T-Cell Leukemia/Lymphoma,
Location: Columbus OH
Sponsor: John Reneau

Sex: All

Age: 18+

Code: NCT04848064

Phase1, Recruiting

Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours

for
Neuroendocrine Tumors
Location: Ottawa, Toronto, London, Regina, Saskatoon, Edmonton,
Sponsor: Australasian Gastro-Intestinal Trials Group

Sex: All

Age: 18+

Code: NCT06345079

Phase2, Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

for
Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT05724121

Recruiting