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SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome,
Location: Boston MA, Houston TX, Duarte CA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT03113643

Phase1, Recruiting

Prospective Observational Study of Outcomes After Gemcitabine, Docetaxel, Melphalan, and Carboplatin With Autologous Stem Cell Transplantation in Pediatric Relapsed/Refractory Germ Cell Tumors

for
Prospective Observational Study, Gemcitabine, Docetaxel,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 21+

Code: NCT07662018

Recruiting

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers

for
Endometrial Clear Cell Adenocarcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05049538

Recruiting

Characterization of the Microbiome in Cutaneous T Cell Lymphoma

for
Cutaneous T Cell Lymphoma
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18 - 70+

Code: NCT03932279

Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

for
Acute Leukemia, Acute Lymphoblastic Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0+

Code: NCT04195633

Phase2, Recruiting

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Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

for
Hairy Cell Leukemia (HCL), Chronic Lymphocytic Leukemia (CLL),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT01087333

Recruiting

CAR T-cell Therapy in Patients With Renal Dysfunction

for
Non-hodgkin Lymphoma,B Cell, Multiple Myeloma,
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18+

Code: NCT05909059

Phase2, Recruiting

Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

for
Hematologic Malignancy, Solid Tumor, Sickle Cell Disease,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 8+

Code: NCT06689800

Recruiting

Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Carcinoma
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT04696575

Phase2, Recruiting

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia, T-cell Lymphoblastic Lymphoma
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 15+

Code: NCT06446661

Recruiting

Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Charlottesville VA, Ann Arbor MI, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT03523975

Phase1, Phase2, Recruiting

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Los Angeles CA, Davis CA, San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06252675

Phase2, Recruiting

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

for
Neurofibroma, Plexiform,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 3 - 35

Code: NCT02390752

Phase1, Recruiting

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for
Grade 3b Follicular Lymphoma, High Grade B-Cell Lymphoma,
Location: New York NY, Richmond VA, Webster NY, Rochester NY,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05890352

Phase2, Recruiting

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

for
Carcinoma, Non-Small-Cell Lung
Location: Lebanon NH, Philadelphia PA, Columbus OH, Houston TX,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT04165070

Phase1, Phase2, Recruiting

Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

for
B-cell Lymphoma, Burkitt Lymphoma,
Location: Valhalla NY
Sponsor: New York Medical College

Sex: All

Age: 12 - 70

Code: NCT04491370

Phase1, Phase2, Recruiting

Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia

for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT04984551

Phase2, Recruiting

Screening Strategies Among High-risk Populations for Anal Cancer

for
Neoplasms, HPV-Related Anal Squamous Cell Carcinoma
Location: Miami FL, Atlanta GA
Sponsor: Lisa Flowers

Sex: All

Age: 30 - 70+

Code: NCT06628570

Recruiting

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

for
Metastatic Clear Cell Renal Cell Carcinoma
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07179770

Phase1, Recruiting

Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

for
Follicular Lymphoma, Marginal Zone Lymphoma, B-Cell Lymphoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06350318

Phase2, Recruiting