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Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06731270

Phase2, Recruiting

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for
T-cell Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: New York NY, Philadelphia PA, Norfolk VA,
Sponsor: Allotera Therapeutics

Sex: All

Age: 0+

Code: NCT06514794

Phase2, Recruiting

Ropeginterferon in Patients w/Cutaneous T-Cell Lymphoma (CTCL)

for
Cutaneous T Cell Lymphoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07047885

Phase1, Recruiting

Studies of Dermatologic Diseases Biospecimen Acquisition Protocol

for
Dermatologic Conditions, Healthy Volunteers, Normal Volunteers,
Location: Bethesda MD
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All

Age: 0 - 70+

Code: NCT02471352

Recruiting

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

for
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06859008

Phase1, Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Bath ME, Portland ME, Scarborough ME, Sanford ME,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase3, Recruiting

Pembrolizumab + N-803 Alone or in Combination With PD-L1 t-haNK Cells for Resectable Head and Neck Squamous Cell Carcinoma

for
Stage II Squamous Cell Carcinoma of the Head and Neck,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161545

Phase2, Recruiting

Exercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial

for
Lung Non-Small Cell Carcinoma
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06983899

Recruiting

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for
Small Cell Lung Carcinoma,
Location: Boston MA, Montreal, Royal Oak MI, Iowa City IA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07006727

Phase1, Recruiting

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

for
Renal Cell Carcinoma, Urothelial Carcinoma,
Location: Boston MA, Philadelphia PA, Cleveland OH, Ann Arbor MI,
Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All

Age: 18+

Code: NCT06966024

Phase1, Recruiting

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for
Chronic Lymphocytic Leukemia, Leukemia, Lymphocytic,
Location: Quebec, Bethesda MD, Richmond VA, West Palm Beach FL,
Sponsor: Loxo Oncology, Inc.

Sex: All

Age: 18+

Code: NCT05254743

Phase3, Recruiting

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1

for
Non-small Cell Lung Cancer
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT06579196

Phase1, Phase2, Recruiting

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

for
Non-small Cell Lung Cancer
Location: Westbrook ME, Farmington CT, Stamford CT, Hackensack NJ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07190248

Phase3, Recruiting

Enhancing Oral Cancer Awareness

for
Oral Cancer, Chatbot, Patient Education, Prevention,
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT06682494

Recruiting

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

for
Non-Small-Cell Lung Cancer,
Location: Lake Success NY, New York NY, Philadelphia PA, Ottawa,
Sponsor: ArriVent BioPharma, Inc.

Sex: All

Age: 18+

Code: NCT07185997

Phase3, Recruiting

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

for
Anaplastic Lymphoma Kinase, Anaplastic Large Cell Lymphoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07001384

Phase1, Recruiting

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

for
Non Small Cell Lung Cancer
Location: Detroit MI
Sponsor: Nerissa T. Viola

Sex: All

Age: 18+

Code: NCT06439914

Phase1, Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

for
Buccal Mucosa Squamous Cell Carcinoma,
Location: New Haven CT, Lebanon NH, Commack NY, Trumbull CT,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT04333537

Phase2, Phase3, Recruiting

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)

for
Non Small Cell Lung Cancer
Location: New York NY
Sponsor: Dizal Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06905197

Phase1, Recruiting

Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

for
Healthy Subject, Hematologic and Lymphocytic Disorder,
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 19+

Code: NCT03207854

Recruiting