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DRP-104 in Patients With NFE2L2/KEAP1-altered Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07249372

Phase2, Recruiting

Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell

for
Renal Cell Carcinoma (Kidney Cancer)
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07062549

Phase1, Recruiting

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

for
Recurrent Diffuse Large B-Cell Lymphoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06784726

Phase2, Recruiting

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

for
NSCLC (Advanced Non-small Cell Lung Cancer), HNSCC,
Location: Fairfax VA, Tampa FL, Farmington Hills MI,
Sponsor: ALX Oncology Inc.

Sex: All

Age: 18+

Code: NCT07085091

Phase1, Recruiting

A Study of Lorigerlimab in Participants With Advanced Solid Tumors

for
Platinum-resistant Ovarian Cancer,
Location: Montreal, Toronto, Pittsburgh PA, Grand Rapids MI,
Sponsor: MacroGenics

Sex: Female

Age: 18+

Code: NCT06730347

Phase2, Recruiting

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Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04780568

Phase1, Recruiting

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

for
Small-cell Lung Cancer, Brain Metastases
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18+

Code: NCT07175077

Recruiting

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

for
Non-Hodgkin Lymphoma Refractory/ Relapsed,
Location: New York NY, Buffalo NY, Nashville TN, St Louis MO,
Sponsor: LTZ Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07121946

Phase1, Recruiting

Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma

for
Ivonescimab, Clear Cell Renal Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06940518

Phase2, Recruiting

A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy

for
Germ Cell Tumor, Testicular Cancer
Location: Charlotte NC, Winston-Salem NC, Milwaukee WI
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70

Code: NCT06866964

Phase2, Recruiting

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

for
Cutaneous Squamous Cell Carcinoma,
Location: Uniondale NY, New York NY, Middletown NJ, Montvale NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05859074

Phase1, Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

Treating Basal and Squamous Cell Carcinomas With Fractional Laser and Tirbanibulin Ointment

for
Keratinocyte Carcinoma, Basal Cell Carcinomas,
Location: New York NY
Sponsor: Bruce Robinson, MD

Sex: All

Age: 18+

Code: NCT07010692

Phase1, Phase2, Recruiting

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for
Extensive-stage Small-cell Lung Cancer
Location: Burlington MA, White Plains NY, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712355

Phase3, Recruiting

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for
Recurrent Langerhans Cell Histiocytosis,
Location: Halifax, Hartford CT, New Haven CT, Quebec, Sherbrooke,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 22

Code: NCT05828069

Phase2, Recruiting

Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain

for
Oral Cancer, Squamous Cell Carcinoma
Location: New York NY
Sponsor: New York University

Sex: All

Age: 18+

Code: NCT07095608

Recruiting

A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Disease

for
NSCLC, NSCLC, Stage I, NSCLC Stage II,
Location: Commack NY, Uniondale NY, East White Plains NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07323732

Phase2, Recruiting

A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Bel Air MD, Glen Burnie MD, Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06800339

Phase1, Recruiting

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

for
Pleuropulmonary Blastoma, Cystic Nephroma,
Location: Bethesda MD, Rockville MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 70+

Code: NCT01247597

Recruiting

Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ICP-248 as Monotherapy or in Combination With Anti-CD20 Monoclonal Antibody in Mature B-cell Malignancies

for
Mature B-cell Malignancies
Location: Westbury NY, Plantation FL
Sponsor: InnoCare Pharma Inc.

Sex: All

Age: 18+

Code: NCT06351527

Phase1, Recruiting