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Hyperfractionated Dual Equivalent Fractionated Radiation Therapy

for
Diffuse Large B-Cell Lymphoma
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT06898905

Recruiting

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

for
Solid Tumor, Small Cell Lung Cancer (SCLC),
Location: Fort Worth TX, West Valley City UT, Los Angeles CA
Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07517198

Phase1, Recruiting

Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

for
Squamous Cell Carcinoma Head and Neck Cancer (HNSCC),
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT07149207

Phase2, Recruiting

UBX-303061 in Subjects With Relapsed/Refractory B-Cell Malignancies

for
Relapsed/Refractory B-cell Malignancies
Location: Canton OK, Ann Arbor MI, Houston TX
Sponsor: Ubix Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06590961

Phase1, Recruiting

Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

for
Breast Cancer, Lung Cancer, Melanoma, Gynecologic Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07524114

Recruiting

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Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

for
Breast Cancer, Lung Cancer, Gastrointestinal Cancer,
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT04273061

Phase2, Recruiting

Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for
GEP-NET, Gastroenteropancreatic Neuroendocrine Tumor,
Location: Montreal, Charlottesville VA, Toronto, Jacksonville FL,
Sponsor: RayzeBio, Inc.

Sex: All

Age: 18+

Code: NCT07165132

Phase1, Recruiting

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

for
HNSCC, HNSCC,Larynx, Pharynx and Oral Cavity,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06819228

Phase1, Recruiting

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

for
KRAS-mutant Non-small Cell Lung Cancer (NSCLC),
Location: Boston MA, Philadelphia PA, Fairfax VA, Tampa FL,
Sponsor: Kestrel Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07458347

Phase1, Recruiting

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

for
Metastatic Renal Cell Carcinoma, Metastatic Renal Cancer,
Location: Boston MA
Sponsor: Stephanie Berg

Sex: All

Age: 18+

Code: NCT07123090

Phase2, Recruiting

A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for
ALK-positive NSCLC, ALK-Positive Lung Cancer,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: TRIANA Biomedicines, Inc.

Sex: All

Age: 18+

Code: NCT07491497

Phase1, Phase2, Recruiting

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer,
Location: Baltimore MD, Washington D.C. DC, Jacksonville FL,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07154290

Phase2, Recruiting

A Study of Navlimetostat (BMS-986504) in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, New York NY, Canton OH, Detroit MI,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06855771

Phase2, Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Quebec, Westbury NY, New York NY, Montreal, Norfolk VA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07361497

Phase3, Recruiting

Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

for
Non Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer,
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05681780

Phase1, Recruiting

Safety and Effectiveness of the HIT Reverse HRS

for
Degenerative Joint Disease, Osteoarthritis, Hip,
Location: Somers Point NJ, Miami FL, Tampa FL, New Albany OH
Sponsor: Hip Innovation Technology

Sex: All

Age: 50 - 70+

Code: NCT05357378

Recruiting

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

for
Non-Small-Cell Lung, Esophageal Cancer, Cutaneous Melanoma
Location: New Haven CT, Trumbull CT, Fairfax VA, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07519655

Phase1, Recruiting

The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors

for
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 39

Code: NCT04551378

Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for
Non-small Cell Lung Cancer (NSCLC)
Location: Halifax, Moncton, South Portland ME, Boston MA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07291037

Phase3, Recruiting

Supportive Care Intervention for Outpatient Stem Cell Transplant Patients

for
Hematopoietic Stem Cell Transplantation, Cancer
Location: Boston MA
Sponsor: Victor Wang

Sex: All

Age: 19+

Code: NCT06564233

Recruiting