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Rare Kidney Stone Consortium Biobank

for
Primary Hyperoxaluria, Dent Disease, APRT Deficiency,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0+

Code: NCT02026388

Recruiting

Prospective Research Rare Kidney Stones (ProRKS)

for
Hyperoxaluria, Cystinuria, Dent Disease, Lowe Syndrome,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0+

Code: NCT02780297

Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for
Hematologic Disorder, Bleeding Disorder,
Location: Scarborough ME, Providence RI, Hartford CT,
Sponsor: American Thrombosis and Hemostasis Network

Sex: All

Age: 0+

Code: NCT04398628

Recruiting

Genomic Investigation of Unusual Responders

for
Cancer, Breast Cancer, Non-small Cell Lung Cancer,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT03740503

Recruiting

Rare and Atypical Diabetes Network

for
Diabetes Mellitus, Diabetes Mellitus Progression,
Location: Boston MA, Brooklyn NY, New York NY, Baltimore MD,
Sponsor: University of South Florida

Sex: All

Age: 0+

Code: NCT05544266

Recruiting

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CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

for
Cancer, Malignancies Multiple, Malignant Solid Tumor,
Location: Halifax, Fredericton, Sherbrooke, Montreal, Ottawa,
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04151342

Recruiting

Rare CFTR Mutation Cell Collection Protocol (RARE)

for
Cystic Fibrosis
Location: Birmingham AL
Sponsor: George Solomon

Sex: All

Age: 17+

Code: NCT03161808

Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for
Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06342414

Recruiting

Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions

for
Dyslipidemia, Atherosclerosis
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 10 - 70+

Code: NCT06676046

Recruiting

International Rare Brain Tumor Registry

for
Astroblastoma, BCOR ITD Sarcoma, CNS Sarcoma,
Location: Washington D.C. DC, Akron OH, Cincinnati OH, Chicago IL,
Sponsor: Children's National Research Institute

Sex: All

Age: 0 - 45

Code: NCT05697874

Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

for
Malignant Solid Tumors, Other Neoplasms Solid Tumors,
Location: Bethesda MD, Houston TX, Portland OR
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT03739827

Recruiting

A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

for
Lung Cancer, Adjuvant, Post-surgical, EGFR, Exon 20,
Location: New York NY, Washington D.C. DC, Fairfax VA, Margate FL,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT07128199

Phase 3, Recruiting

Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

for
Adenocarcinoma of the Bladder,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06041503

Phase 2, Recruiting

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

for
Non-Small-Cell Lung Cancer,
Location: Lake Success NY, New York NY, Philadelphia PA, Ottawa,
Sponsor: ArriVent BioPharma, Inc.

Sex: All

Age: 18+

Code: NCT07185997

Phase 3, Recruiting

Influencing Next-Generation Oncologic Outcomes Through Rapid Integration of Functional Precision Medicine (NOORI): A Feasibility Study of SmartMatch in Rare Gynecologic Cancers

for
Malignant Female Reproductive System Neoplasm,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: Female

Age: 18+

Code: NCT07731880

Recruiting

Y-90 Treatment Response Using Transarterial Radioembolization

for
HCC, Hepatocellular Carcinoma, Liver Cancer, Hepatic Neoplasm,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT07145801

Phase 2, Recruiting

Rare Tumors and Cancer Predisposition in Individuals and Families

for
Cancer, Hereditary Neoplasms, Genetic Predisposition to Cancer,
Location: Bethesda MD, Rockville MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 70+

Code: NCT05350761

Recruiting

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

for
Liver and Intrahepatic Bile Duct Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04982653

Phase 2, Recruiting

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

for
Urothelial Cancer, Bladder Cancer, Genitourinary Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04923178

Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

for
Liver Neoplasms, Primary Liver Cancer, Secondary Liver Cancer,
Location: Boston MA, Manhasset NY, New York NY, Allentown PA,
Sponsor: HistoSonics, Inc.

Sex: All

Age: 22+

Code: NCT06486454

Recruiting