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A Study to Investigate Fadraciclib (CYC065), in Subjects With Advanced Solid Tumors and Lymphoma

for
Solid Tumor, Adult, Lymphoma
Location: Houston TX, Duarte CA
Sponsor: Cyclacel Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT04983810

Phase1, Phase2, Recruiting

Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors

for
Solid Tumors, Adult
Location: Irving TX, San Antonio TX
Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Sex: All

Age: 18+

Code: NCT06504368

Phase1, Recruiting

COAST Therapy in Advanced Solid Tumors and Prostate Cancer

for
Prostate Cancer Recurrent, Solid Tumor, Adult
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05036226

Phase1, Phase2, Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

for
Solid Tumor, Adult, Carcinoma, Ovarian Epithelial,
Location: Silver Spring MD, Detroit MI, Houston TX, Dallas TX
Sponsor: Bio-Path Holdings, Inc.

Sex: All

Age: 18+

Code: NCT04196257

Phase1, Recruiting

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention

for
Solid Tumor, Adult
Location: Chico CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06436157

Recruiting

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A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

for
Lung Cancer, Non-small Cell, Lung Cancer Metastatic,
Location: Weston FL, Canton OH, Cleveland OH, Detroit MI,
Sponsor: Krystal Biotech, Inc.

Sex: All

Age: 18+

Code: NCT06228326

Phase1, Phase2, Recruiting

A Tissue Collection Study in Patients Who Respond to Immune Checkpoint Inhibitors to Identify Targets of Tumor-Reactive T Cells.

for
Solid Tumor, Adult
Location: New York NY, Morristown NJ, New Orleans LA,
Sponsor: TScan Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05230186

Recruiting

A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

for
Solid Tumor, Adult, Healthy Donors, COVID-19 Donors
Location: Huntersville NC
Sponsor: BioCytics, Inc.

Sex: All

Age: 5+

Code: NCT00571389

Recruiting

A Beta-only IL-2 ImmunoTherapY Study

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boca Raton FL, Toronto, Detroit MI, Atlanta GA,
Sponsor: Medicenna Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05086692

Phase1, Phase2, Recruiting

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for
Solid Tumor, Adult, Triple Negative Breast Cancer,
Location: Scottsdale AZ, La Jolla CA, Stanford CA
Sponsor: BioEclipse Therapeutics

Sex: All

Age: 18+

Code: NCT04282044

Phase1, Recruiting

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

for
Rectal Adenocarcinoma, Clinical Stage: Stage II (T3-4, N-),
Location: Hartford CT, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04165772

Phase2, Recruiting

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for
Solid Tumor, Adult, Refractory Cancer,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: GV20 Therapeutics

Sex: All

Age: 18+

Code: NCT05669430

Phase1, Phase2, Recruiting

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

for
Solid Tumor, Adult
Location: Boston MA, New Haven CT, Orlando FL, Birmingham AL,
Sponsor: Corbus Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT06265727

Phase1, Phase2, Recruiting

First In Human Study of CX-801 in Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Pittsburgh PA, Nashville TN, Fort Worth TX,
Sponsor: CytomX Therapeutics

Sex: All

Age: 18+

Code: NCT06462794

Phase1, Recruiting

Phase 1 Study of RBN-2397, an Oral PARP7 Inhibitor, in Patients With Solid Tumors

for
Solid Tumor, Adult
Location: Boston MA, New Haven CT, Pittsburgh PA, Orlando FL,
Sponsor: Ribon Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04053673

Phase1, Recruiting

Safety and Tolerability of HTI-1066 in Subjects With Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Scottsdale AZ
Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: All

Age: 18+

Code: NCT03398720

Phase1, Recruiting

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

for
Solid Tumor, Adult
Location: Washington D.C. DC, Florida City FL, Huntersville NC,
Sponsor: DualityBio Inc.

Sex: All

Age: 18+

Code: NCT06554795

Phase1, Phase2, Recruiting

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

for
PIK3CA Mutations, Advanced Solid Tumors, Adult,
Location: Boston MA, East Brunswick NJ, Fairfax VA, Tampa FL,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07383506

Phase1, Recruiting

A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

for
Solid Tumors, Adult
Location: Plantation FL, Cleveland OH, Denver CO
Sponsor: Hutchmed

Sex: All

Age: 18+

Code: NCT07228247

Phase1, Phase2, Recruiting

DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

for
Solid Tumor, Solid Tumor, Adult
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 21 - 70+

Code: NCT07225088

Recruiting