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A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

for
Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
Location: New York NY, New Brunswick NJ, Morristown NJ,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT04913285

Phase1, Recruiting

Psychotherapy Intervention for Latinos With Advanced Cancer

for
Solid Tumor, Solid Tumor, Adult,
Location: The Bronx NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04015609

Recruiting

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

for
Solid Tumor, Adult, Malignant Solid Tumor,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06824363

Early_phase1, Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06218914

Phase1, Recruiting

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

for
Solid Tumor, Adult, Solid Tumor, Melanoma, Basal Cell Cancer,
Location: Denver CO, Nashville TN
Sponsor: Rise Therapeutics LLC

Sex: All

Age: 18 - 70+

Code: NCT06398418

Phase1, Recruiting

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Intravital Microscopy in Human Solid Tumors

for
Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03823144

Recruiting

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07020221

Phase1, Phase2, Recruiting

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

for
Cancer, Solid Tumor, Adult, Cancer Metastatic, Solid Carcinoma,
Location: San Antonio TX
Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

Sex: All

Age: 18+

Code: NCT04443088

Phase1, Recruiting

A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors

for
Solid Tumor, Adult, Advanced Solid Tumor, Advanced Cancer,
Location: Boston MA, New York NY, Houston TX, San Antonio TX,
Sponsor: Monopteros Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04859777

Phase1, Recruiting

Study of ON 123300 in Patients With Advanced Cancer

for
Solid Tumors, Adult
Location: Greenville SC, Grand Rapids MI, Dallas TX
Sponsor: Traws Pharma, Inc.

Sex: All

Age: 18+

Code: NCT04739293

Phase1, Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for
Oncology, MEK Mutation, RAF Gene Mutation,
Location: New York NY, Fairfax VA, Buffalo NY, Pittsburgh PA,
Sponsor: Nested Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06326411

Phase1, Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for
Metastatic Hepatocellular Carcinoma, Solid Tumors,
Location: Boston MA, New York NY, Baltimore MD, Toronto,
Sponsor: Tyra Biosciences, Inc

Sex: All

Age: 18+

Code: NCT06915753

Phase1, Recruiting

A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Los Angeles CA
Sponsor: BioInvent International AB

Sex: All

Age: 18+

Code: NCT04219254

Phase1, Phase2, Recruiting

A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors

for
Solid Tumor, Adult, Colorectal Cancer,
Location: Houston TX
Sponsor: Crossignal Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06598007

Phase1, Phase2, Recruiting

First In Human Study of CX-2051 in Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Boston MA, The Bronx NY, Fairfax VA, Huntersville NC,
Sponsor: CytomX Therapeutics

Sex: All

Age: 18+

Code: NCT06265688

Phase1, Recruiting

Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors

for
Solid Tumor, Adult, Oncology
Location: Huntersville NC, Santa Monica CA
Sponsor: Trethera

Sex: All

Age: 18+

Code: NCT05055609

Phase1, Recruiting

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for
Advanced Solid Tumors With KRAS G12C Mutations,
Location: Boston MA, Philadelphia PA, Fairfax VA, Detroit MI,
Sponsor: Frontier Medicines Corporation

Sex: All

Age: 18+

Code: NCT06244771

Phase1, Phase2, Recruiting

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

for
Sarcoma, Solid Tumor, Adult, Solid Tumor, Childhood
Location: Valhalla NY, The Bronx NY, Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 1 - 40

Code: NCT03465592

Phase1, Phase2, Recruiting

Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies

for
Solid Tumor, Adult
Location: Commack NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Effector Therapeutics

Sex: All

Age: 18+

Code: NCT04092673

Phase1, Phase2, Recruiting

Cisplatin, Gemcitabine, Interferon Alfa, and Hyperthermia in Treating Patients With Advanced Cancer

for
Unspecified Adult Solid Tumor, Protocol Specific
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT00004063

Phase1, Phase2, Recruiting