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Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase1, Phase2, Recruiting
Active & Responsive

Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

for
Advanced Solid Tumor
Location: Pittsburgh PA, Houston TX, Beverly Hills CA
Sponsor: Strand Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06249048

Phase1, Phase2, Recruiting
Active & Responsive

A Study of PHST001 in Advanced Solid Tumors

for
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Pheast Therapeutics

Sex: All

Age: 18+

Code: NCT06840886

Phase1, Recruiting
Active & Responsive

Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

for
Solid Tumor
Location: Pittsburgh PA, Atlanta GA, St Louis MO, Houston TX
Sponsor: Emory University

Sex: All

Age: 1 - 30

Code: NCT04469530

Phase2, Recruiting
Active & Responsive

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

for
Somatostatin Receptor Positive, NETs, Lymphoma, Solid Tumor,
Location: Philadelphia PA, Houston TX, San Francisco CA
Sponsor: ITM Solucin GmbH

Sex: All

Age: 2 - 18

Code: NCT06441331

Phase1, Recruiting

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Active & Responsive

A Study in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration Resistant Prostate Cancer, mCRPC,
Location: East Brunswick NJ, Fairfax VA, Myrtle Beach SC,
Sponsor: Flare Therapeutics Inc.

Sex: Male

Age: 18+

Code: NCT07719361

Phase1, Recruiting
Active & Responsive

Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.

for
Reccurent/Metastatic Solid Tumor Disease,
Location: Quebec
Sponsor: CHU de Quebec-Universite Laval

Sex: Male

Age: 18+

Code: NCT07483658

Recruiting
Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting
Active & Responsive

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

for
Solid Tumors
Location: St. Petersburg FL, Germantown TN, Rochester MN,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07415031

Phase2, Recruiting
Active & Responsive

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for
FGFR2 Gene Fusion/Rearrangement, Other Solid Tumors, Adult
Location: Boston MA, New York NY, Tampa FL, Chicago IL,
Sponsor: Elevar Therapeutics

Sex: All

Age: 18+

Code: NCT07359820

Phase2, Recruiting
Active & Responsive

A Study of TAK-505 in Adults With Solid Tumors

for
Malignant Solid Tumors
Location: Fairfax VA, Tampa FL, Nashville TN, Minneapolis MN,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07436728

Phase1, Phase2, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Norwich CT, Fairfax VA, Nashville TN, Saint Paul MN,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07397338

Phase1, Phase2, Recruiting
Active & Responsive

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

for
Solid Tumors (Phase 1), RAS Mutation
Location: Orlando FL, Houston TX
Sponsor: Adlai Nortye Biopharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT07252479

Phase1, Recruiting
Active & Responsive

FIH Study to Evaluate Safety, Tolerability, PK, PD & Preliminary Efficacy of AT03-65 With Advanced Solid Tumors

for
Solid Tumor
Location: Portland OR
Sponsor: Axcynsis Therapeutics Pte Ltd

Sex: All

Age: 18+

Code: NCT06809114

Phase1, Recruiting
Active & Responsive

Study of PAT in Patients With Solid Tumor Cancers

for
Metastasis, Solid Tumor
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT05338658

Phase1, Recruiting
Active & Responsive

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: New Haven CT, Philadelphia PA, Fairfax VA,
Sponsor: Ipsen

Sex: All

Age: 18+

Code: NCT07213817

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

for
Advanced Solid Tumor, Metastatic Solid Tumor
Location: Toronto, Grand Rapids MI, Nashville TN, Houston TX,
Sponsor: Ipsen

Sex: All

Age: 18+

Code: NCT07213830

Phase1, Phase2, Recruiting
Active & Responsive

The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

for
Metastatic Solid Tumors, Stage 4 Cancer
Location: Rochester MN
Sponsor: New Phase Ltd.

Sex: All

Age: 18+

Code: NCT07224464

Recruiting
Active & Responsive

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for
Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT07514819

Recruiting