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Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

for
Cancer, Solid Tumor Cancer, Advanced Metastatic Cancer,
Location: Fairfax VA, Plantation FL, Austin TX, San Antonio TX
Sponsor: Conjupro Biotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07424547

Phase1, Recruiting

Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss

for
Advanced Cancer, Solid Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07382544

Phase1, Recruiting

Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: New Haven CT, Lake Success NY, Grand Rapids MI
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07387068

Phase1, Recruiting

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, New Haven CT, Baltimore MD, Birmingham AL,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07226349

Phase1, Recruiting

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

for
Refractory Solid Tumor, Hepatocellular Carcinoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 30

Code: NCT05468359

Phase1, Phase2, Recruiting

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WellSpan-THRIVE Cancer QOL Study

for
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative,
Location: Ephrata PA, Lebanon PA, York PA, Gettysburg PA,
Sponsor: WellSpan Health

Sex: All

Age: 18+

Code: NCT07433660

Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

for
Renal Cell Carcinoma (RCC),
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05176483

Phase1, Recruiting

BTM-3566 in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Houston TX, San Antonio TX
Sponsor: Bantam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07266285

Phase1, Recruiting

A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, New Haven CT, Grand Rapids MI,
Sponsor: Ottimo Pharma Limited

Sex: All

Age: 18+

Code: NCT07266428

Phase1, Phase2, Recruiting

A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation

for
Advanced Solid Tumors
Location: Fort Myers FL, Houston TX
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT07172919

Phase2, Recruiting

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

for
Seizures, Primary Motor Cortex,
Location: Boston MA
Sponsor: Ayal A. Aizer, MD

Sex: All

Age: 18+

Code: NCT07130786

Phase2, Recruiting

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

for
Brain Metastases, Adult, Brain Tumor - Metastatic,
Location: Boston MA
Sponsor: Ayal A. Aizer, MD

Sex: All

Age: 18+

Code: NCT07132190

Phase2, Recruiting

DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

for
Solid Tumor, Solid Tumor, Adult
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 21 - 70+

Code: NCT07225088

Recruiting

A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

for
Locally Advanced or Metastatic Malignant Solid Tumors
Location: New Hyde Park NY, Hackensack NJ, Fairfax VA,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07287995

Phase1, Phase2, Recruiting

A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

for
Melanoma, Metastatic Melanoma, Advanced Solid Tumor,
Location: La Jolla CA
Sponsor: Replimune Inc.

Sex: All

Age: 18+

Code: NCT06887348

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

for
Lung Cancer (NSCLC), Prostate Cancer, Esophageal Cancer,
Location: Orlando FL, Nashville TN, Houston TX
Sponsor: Phrontline Biopharma

Sex: All

Age: 18+

Code: NCT07181473

Phase1, Recruiting

DPTX3186 in Wnt Pathway Activated Solid Tumors

for
Solid Tumors
Location: Fairfax VA, San Antonio TX
Sponsor: Dewpoint Therapeutics

Sex: All

Age: 18+

Code: NCT07312903

Phase1, Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Frederick MD, St Louis MO, Springfield MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

A Study of YL242 in Subjects With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Sarasota FL, Grand Rapids MI, Nashville TN
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All

Age: 18+

Code: NCT07197827

Phase1, Phase2, Recruiting

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

for
Cancer, Cancer (Solid Tumors)
Location: Fairfax VA, Huntersville NC, Dallas TX
Sponsor: Conjupro Biotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07317505

Phase1, Recruiting