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A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

for
Invasive Ductal Breast Carcinoma,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05837767

Recruiting

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for
Solid Tumors, Hematologic Malignancies
Location: Quebec, Sherbrooke, White Plains NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT03486873

Phase3, Recruiting

A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors

for
Refractory Solid Tumors
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 1 - 25

Code: NCT06006273

Phase1, Recruiting

AMT-116 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Dallas TX
Sponsor: Multitude Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT05725291

Phase1, Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

for
Breast Cancer, Breast Cancer Metastatic,
Location: Boston MA, Durham NC, Buffalo NY, Orlando FL,
Sponsor: Incyclix Bio

Sex: All

Age: 18+

Code: NCT05735080

Phase1, Phase2, Recruiting

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ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC

for
Solid Tumors, EGFR Exon 20 Insertion Mutations, NSCLC,
Location: New York NY, Fairfax VA
Sponsor: ORIC Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06816992

Phase1, Recruiting

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

for
Advanced Cancer, Anal Carcinoma, Anal Cancer, Biliary Cancer,
Location: New Brunswick NJ
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT02628067

Phase2, Recruiting

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

for
Advanced Solid Tumor, Metastatic Solid Tumor
Location: Houston TX
Sponsor: SOTIO Biotech AG

Sex: All

Age: 18+

Code: NCT06163391

Phase1, Recruiting

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

for
HER2-positive Advanced Solid Tumor
Location: Boston MA, Shirley NY, Lake Success NY, New York NY,
Sponsor: DualityBio Inc.

Sex: All

Age: 18+

Code: NCT05150691

Phase1, Phase2, Recruiting

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

for
Sarcoma, Solid Tumor, Adult, Solid Tumor, Childhood
Location: Valhalla NY, The Bronx NY, Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 1 - 40

Code: NCT03465592

Phase1, Phase2, Recruiting

Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies

for
Solid Tumor, Adult
Location: Commack NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Effector Therapeutics

Sex: All

Age: 18+

Code: NCT04092673

Phase1, Phase2, Recruiting

Immune Resistance Interrogation Study

for
Cancer, Solid Tumor, Metastatic Cancer, Immune Resistance
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04243720

Recruiting

A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Cincinnati OH
Sponsor: Jubilant Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT05268666

Phase1, Phase2, Recruiting

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Fairfax VA, Irving TX, Austin TX, San Antonio TX
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT06090266

Phase1, Phase2, Recruiting
New

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

for
Malignant Solid Neoplasm
Location: Vancouver WA, Longview WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06771739

Recruiting
New

Community Enhanced Virtual Informed Consent

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07805083

Recruiting

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05039632

Phase1, Phase2, Recruiting

Immune Profiling for Cancer Immunotherapy Response

for
Cancer, Tumor, Solid, Hematologic Malignancy, Blood Cancer
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18+

Code: NCT06116032

Recruiting

Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06015932

Recruiting

Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

for
Metastatic Malignant Solid Neoplasm, Lymphoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05371132

Phase1, Recruiting