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SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

for
Metastatic Malignant Neoplasm in the Brain,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05222620

Phase2, Recruiting
New

Sacituzumab Tirumotecan +/- Pembrolizumab in I/O Exposed Metastatic or Recurrent Ovarian Clear Cell Cancer

for
Ovarian Clear Cell Carcinoma, Metastatic Ovarian Cancer,
Location: Boston MA
Sponsor: Tufts Medical Center

Sex: Female

Age: 18+

Code: NCT07718854

Phase2, Recruiting

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

for
Advanced Thyroid Gland Medullary Carcinoma,
Location: Houston TX, San Francisco CA
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04216732

Recruiting

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

for
Small Cell Carcinoma of the Bladder,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161532

Phase2, Recruiting

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

for
Non-small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer,
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18+

Code: NCT02838836

Recruiting

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Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

for
Human Immunodeficiency Virus, End Stage Renal Disease
Location: Metairie LA
Sponsor: Tulane University

Sex: All

Age: 18+

Code: NCT05159466

Recruiting

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

for
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers,
Location: Montreal, Ottawa, Toronto, Hamilton, Edmonton
Sponsor: Bold Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04421820

Phase1, Phase2, Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

for
Gastric Cancer, Gastroesophageal Junction Cancer,
Location: Providence RI, Sherbrooke, Commack NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06219941

Phase2, Recruiting

Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100

for
Ovarian Clear Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06065462

Phase1, Phase2, Recruiting

Definitive Therapy for Oligometastatic Solid Malignancies

for
Stage IV or Recurrent Carcinoma or Sarcoma
Location: Aurora CO, Thornton CO, Littleton CO, Boulder CO
Sponsor: Rocky Mountain Cancer Centers

Sex: All

Age: 18+

Code: NCT01898962

Phase2, Recruiting

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

for
Hepatocellular Carcinoma
Location: St Louis MO, Houston TX, Los Angeles CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06795022

Phase1, Phase2, Recruiting

Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

for
Non-Medullary Thyroid Cancer
Location: Bethesda MD
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 7 - 70+

Code: NCT01109420

Recruiting

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer,
Location: Boston MA, Commack NY, Baltimore MD, Ottawa, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05123482

Phase1, Phase2, Recruiting

BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants

for
Chronic Kidney Disease, Stage 4,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18 - 65

Code: NCT06741072

Phase1, Recruiting

GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours

for
Alveolar Soft Part Sarcoma, Renal Cell Carcinoma,
Location: Toronto, Calgary
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 15+

Code: NCT07297667

Phase1, Recruiting

Cultural Adaptation of an Educational Tool in Medullary Thyroid Cancer

for
Medullary Thyroid Cancer (MTC), Cultural Adaptation
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07142005

Recruiting

Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies

for
Neoplasms
Location: Grand Rapids MI, Chicago IL, San Antonio TX,
Sponsor: Corcept Therapeutics

Sex: All

Age: 18+

Code: NCT07276373

Phase1, Phase2, Recruiting

Retifanlimab and Ruxolitinib In Solid Malignancies

for
Non Small Cell Lung Carcinoma, Renal Cell Carcinoma
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 0+

Code: NCT07219576

Phase1, Phase2, Recruiting

The Gut Microbiome and Immunotherapy Response in Solid Cancers

for
Cancer
Location: Galveston TX
Sponsor: The University of Texas Medical Branch, Galveston

Sex: All

Age: 35 - 70+

Code: NCT06050733

Recruiting

Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma

for
Clear Cell Carcinoma, Phase 1, Growth Factor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07072234

Phase1, Recruiting