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A Study of VET3-TGI in Patients With Solid Tumors

for
Solid Tumor, Adult, Microsatellite Stable Colorectal Cancer,
Location: Miami FL, Pittsburgh PA, Indianapolis IN, Houston TX,
Sponsor: KaliVir Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06444815

Phase1, Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion,
Location: South Portland ME, Boston MA, New Haven CT, New York NY,
Sponsor: Bayer

Sex: All

Age: 0+

Code: NCT04142437

Recruiting

64Cu-GRIP B in Patients With Advanced Malignancies

for
Prostate Cancer, Renal Cancer, Urethral Cancer,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT05888532

Phase1, Phase2, Recruiting

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: New York NY, Jacksonville FL, Cleveland OH,
Sponsor: GI Innovation, Inc.

Sex: All

Age: 18+

Code: NCT05824975

Phase1, Phase2, Recruiting

Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors

for
Solid Tumor
Location: Pittsburgh PA, Edgewood KY, Iowa City IA, Phoenix AZ
Sponsor: Oxford BioTherapeutics Ltd

Sex: All

Age: 18+

Code: NCT04064359

Phase1, Recruiting

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Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors

for
Solid Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06563375

Phase1, Recruiting

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

for
Advanced Solid Tumor, TNBC - Triple-Negative Breast Cancer,
Location: New Haven CT, New York NY, The Bronx NY,
Sponsor: SillaJen, Inc.

Sex: All

Age: 18+

Code: NCT05768932

Phase1, Recruiting

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

for
Advanced Solid Tumor, Non Small Cell Lung Cancer,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Synthekine

Sex: All

Age: 18+

Code: NCT05098132

Phase1, Phase2, Recruiting

Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin

for
Solid Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06576037

Phase1, Recruiting

Combination Therapy in Cancers With Mutations in DNA Repair Genes

for
Metastatic Solid Tumor, BRCA1 Mutation, BRCA2 Mutation,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT05694715

Phase1, Recruiting

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

for
Advanced Unresectable Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, Philadelphia PA, Baltimore MD, Columbus OH,
Sponsor: TopAlliance Biosciences

Sex: All

Age: 18+

Code: NCT04137900

Phase1, Recruiting

Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

for
Carcinoma, Non-Small-Cell Lung Cancer,
Location: Norfolk VA, Pittsburgh PA, Tyler TX, Beverly Hills CA
Sponsor: Kiromic BioPharma Inc.

Sex: All

Age: 18+

Code: NCT06069570

Phase1, Recruiting

Tolerability of Utidelone Capsule in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Los Angeles CA
Sponsor: Biostar Pharma, Inc.

Sex: All

Age: 18+

Code: NCT05681000

Phase1, Recruiting

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Toronto, Pittsburgh PA, Huntersville NC,
Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All

Age: 18+

Code: NCT06480552

Phase1, Recruiting

A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Providence RI, Houston TX
Sponsor: TYK Medicines, Inc

Sex: All

Age: 18+

Code: NCT05769075

Phase1, Recruiting

A Study of ICP-192 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors, Urothelial Carcinoma, Cholangiocarcinoma
Location: Lake Success NY, Bronx NY, Columbus OH, Minneapolis MN,
Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

Sex: All

Age: 18+

Code: NCT04565275

Phase1, Phase2, Recruiting

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for
Solid Tumor, Adult, Metastatic Breast Cancer,
Location: Boston MA, New York NY, Tampa FL, Indianapolis IN,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06625775

Phase1, Recruiting

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

for
Solid Tumor
Location: Providence RI, New York NY, Hackensack NJ, Newark DE,
Sponsor: Sanofi

Sex: All

Age: 18+

Code: NCT05584670

Phase1, Phase2, Recruiting

S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors

for
Solid Tumors
Location: Philadelphia PA, Gainesville FL, Houston TX
Sponsor: Shionogi

Sex: All

Age: 18+

Code: NCT05101070

Phase1, Phase2, Recruiting

YL-13027 in Patients With Advanced Solid Tumors

for
Solid Tumor
Location: Houston TX
Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All

Age: 18+

Code: NCT05228600

Phase1, Recruiting