A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body
Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors
for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors,
Location: Washington D.C. DC, Durham NC, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals
Sex: All
Age: 1 - 70+
Code: NCT05868629
Recruiting
Study of SGR-3515 In Participants With Advanced Solid Tumors.
for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Fairfax VA, Toronto,
Sponsor: Schrödinger, Inc.
Sex: All
Age: 18+
Code: NCT06463340
Phase 1, Recruiting
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First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
for
Solid Tumor
Location: Orlando FL, Nashville TN, Lincoln NE, San Antonio TX
Sponsor: Corbus Pharmaceuticals Inc.
Sex: All
Age: 18+
Code: NCT06603844
Phase 1, Phase 2, Recruiting
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
for
Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06810544
Phase 1, Phase 2, Recruiting
PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors
for
Locally Advanced or Metastatic Solid Tumors
Location: Margate FL, San Antonio TX, Beverly Hills CA
Sponsor: Pyrotech Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06244992
Phase 1, Phase 2, Recruiting
A Beta-only IL-2 ImmunoTherapY Study
for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boca Raton FL, Toronto, Detroit MI, Atlanta GA,
Sponsor: Medicenna Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05086692
Phase 1, Phase 2, Recruiting
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
for
Solid Tumor, Adult, Triple Negative Breast Cancer,
Location: Scottsdale AZ, La Jolla CA, Stanford CA
Sponsor: BioEclipse Therapeutics
Sex: All
Age: 18+
Code: NCT04282044
Phase 1, Recruiting
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
for
Metastatic Solid Tumor, Advanced Solid Tumor
Location: Lake Success NY, New York NY, Fairfax VA, Pittsburgh PA,
Sponsor: Coherus Oncology, Inc.
Sex: All
Age: 18+
Code: NCT06657144
Phase 1, Recruiting
Trial of DFP-14927 in Advanced Solid Tumors
for
Solid Tumor, Cancer
Location: Houston TX, Los Angeles CA
Sponsor: Delta-Fly Pharma, Inc.
Sex: All
Age: 18+
Code: NCT03943004
Phase 1, Recruiting
Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors
for
Rectal Adenocarcinoma, Clinical Stage: Stage II (T3-4, N-),
Location: Hartford CT, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center
Sex: All
Age: 18+
Code: NCT04165772
Phase 2, Recruiting
Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors
for
Advanced Solid Tumor
Location: San Francisco CA
Sponsor: Robert Bok, MD, PhD
Sex: All
Age: 18+
Code: NCT05599048
Phase 1, Phase 2, Recruiting
Registry of Older Patients With Cancer
for
Chronic Myeloproliferative Disorders,
Location: Morehead City NC, New Bern NC, Greenville NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center
Sex: All
Age: 65+
Code: NCT01137825
Recruiting
A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors
for
Advanced Solid Tumor
Location: Providence RI, New Haven CT, Miami FL, Charleston SC,
Sponsor: Eikon Therapeutics
Sex: All
Age: 18 - 70+
Code: NCT06253130
Phase 1, Phase 2, Recruiting
Study of STP938 (Dencatistat) in Advanced Solid Tumours
for
Solid Tumor
Location: St. Petersburg FL, Dallas TX, San Antonio TX
Sponsor: Step Pharma, SAS
Sex: All
Age: 18+
Code: NCT06297525
Phase 1, Recruiting
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
for
Solid Tumor, Adult, Refractory Cancer,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: GV20 Therapeutics
Sex: All
Age: 18+
Code: NCT05669430
Phase 1, Phase 2, Recruiting
ORB-021 In Patients With Advanced Solid Tumors
for
Advanced Solid Tumors Cancer
Location: Houston TX, Scottsdale AZ
Sponsor: Orionis Biosciences Inc
Sex: All
Age: 18+
Code: NCT06607939
Phase 1, Recruiting
Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment
for
Advanced or Metastatic Solid Tumor, Liver Failure
Location: Newark DE, Baltimore MD, Houston TX, San Antonio TX