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ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

for
Solid Tumor, Adult, Malignant Solid Tumor,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06824363

Early Phase 1, Recruiting

PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer

for
Triple Negative Breast Cancer (TNBC),
Location: Toronto, Houston TX, San Antonio TX,
Sponsor: ProteinQure Inc.

Sex: All

Age: 18+

Code: NCT07190469

Phase 1, Recruiting

A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, New York NY, Hackensack NJ, Buffalo NY,
Sponsor: NextCure, Inc.

Sex: All

Age: 18+

Code: NCT06792552

Phase 1, Recruiting

A Study of DS5361b in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Providence RI, Fairfax VA, Sarasota FL, Irving TX,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07182591

Phase 1, Recruiting

Study of GS-5319 Given Alone or in Combination in Adults With Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, Fairfax VA, San Antonio TX
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT07128303

Phase 1, Recruiting

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SLV-324 Treatment of Metastatic Solid Tumors

for
Metastatic Solid Tumors
Location: Philadelphia PA, Cleveland OH, St Louis MO, Houston TX,
Sponsor: Solve Therapeutics

Sex: All

Age: 18+

Code: NCT07108114

Phase 1, Recruiting

5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors

for
Solid Tumor, Locally Advanced Solid Tumor, Metastatic Tumor
Location: Iowa City IA
Sponsor: Mohammed Milhem

Sex: All

Age: 18 - 70+

Code: NCT07404332

Phase 1, Recruiting

A Study of NEOK002, an EGFR and MUC1 Targeting Bispecific ADC, in Participants With Select Solid Tumors

for
Locally Advanced (Unresectable) or Metastatic Solid Tumors
Location: New York NY, Fairfax VA, Orlando FL, Nashville TN,
Sponsor: NEOK Bio, Inc.

Sex: All

Age: 18+

Code: NCT07612189

Phase 1, Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK201 in Participants With Advanced Solid Tumors

for
Advanced Cancer, Advanced Solid Tumors
Location: Orlando FL, Nashville TN, New Orleans LA, Denver CO
Sponsor: Shanghai Allink Biotherapeutics Co., Ltd.

Sex: All

Age: 18 - 70+

Code: NCT06656390

Phase 1, Phase 2, Recruiting

Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

for
HER2-Positive Solid Tumor
Location: Nashville TN
Sponsor: Yuhan Corporation

Sex: All

Age: 18+

Code: NCT05523947

Phase 1, Phase 2, Recruiting

Study of FID-022 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Tampa FL, Duarte CA, Los Angeles CA
Sponsor: Fulgent Pharma LLC.

Sex: All

Age: 18+

Code: NCT06694480

Phase 1, Recruiting

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for
KRAS Altered Advanced or Metastatic Solid Tumors
Location: Boston MA, Montreal, Philadelphia PA, Fairfax VA,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT07094113

Phase 1, Recruiting

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

for
Advanced Solid Tumor
Location: Boston MA, Hartford CT, New Haven CT, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07070232

Phase 1, Phase 2, Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

for
Colon Cancer, Pancreatic Cancer, Lung Cancer (NSCLC),
Location: Boston MA, Washington D.C. DC, Fairfax VA, Durham NC,
Sponsor: Pheon Therapeutics

Sex: All

Age: 18+

Code: NCT07127874

Phase 1, Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

for
Breast Cancer, Ovarian Cancer, Endometrial Cancer,
Location: Fairfax VA, Houston TX, San Antonio TX, Los Angeles CA
Sponsor: Regor Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT07524322

Phase 1, Recruiting

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Toronto, Huntersville NC, Galveston TX, San Antonio TX
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT07360314

Phase 1, Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06218914

Phase 1, Recruiting

A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

for
Advance Solid Tumors
Location: New Have CT, Santa Monica CA
Sponsor: Kivu Bioscience Inc.

Sex: All

Age: 18+

Code: NCT07229313

Phase 1, Recruiting

A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.

for
Advanced Solid Tumors
Location: New Haven CT, Hinsdale IL, Houston TX, Scottsdale AZ,
Sponsor: Sun Pharma Advanced Research Company Limited

Sex: All

Age: 18+

Code: NCT07042100

Phase 1, Recruiting

First-in-Human Study of ADCE-B05 in Patients With Advanced Solid Tumors

for
Solid Tumors (Phase 1)
Location: New Haven CT, Springdale AR, Houston TX
Sponsor: Adcendo ApS

Sex: All

Age: 18+

Code: NCT07362888

Phase 1, Recruiting