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Active & Responsive

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

for
Prostate Cancer Patients, Non-castrate Prostate Cancer,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: Male

Age: 18+

Code: NCT07090148

Phase 1, Recruiting
Active & Responsive

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

for
Melanoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06961357

Phase 1, Phase 2, Recruiting
Active & Responsive

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

for
Brain Neoplasms
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 70+

Code: NCT07111182

Recruiting
Active & Responsive

Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

for
Glioblastoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06831526

Early Phase 1, Recruiting
Active & Responsive

Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma, Uveal Melanoma, Metastatic,
Location: Nashville TN, Denver CO, Scottsdale AZ
Sponsor: Novelwise Pharmaceutical Corporation

Sex: All

Age: 18+

Code: NCT07136181

Phase 1, Phase 2, Recruiting

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Active & Responsive

Maintenance Zanzalintinib With Etoposide After HDCT in GCT

for
Germ Cell Tumor
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT06937866

Phase 1, Phase 2, Recruiting
Active & Responsive

A Pilot Study of Ultra-High Dose Rate (ConformalFLASH®), for Reirradiation of Carcinoma of the Head and Neck

for
Head and Neck Cancer
Location: Philadelphia PA
Sponsor: IBA Proton Therapy, Inc.

Sex: All

Age: 18+

Code: NCT07644585

Recruiting
Active & Responsive

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

for
Pediatric Tumor of CNS, Pediatric Tumor of Brain,
Location: Orange CA
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 5 - 18

Code: NCT06357377

Phase 1, Recruiting
Active & Responsive

A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma

for
Metastatic Urothelial Carcinoma,
Location: Spokane WA, Los Angeles CA
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT07815665

Phase 2, Phase 3, Recruiting
Active & Responsive

CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial

for
HSIL, High Grade Squamous Intraepithelial Lesion,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 21+

Code: NCT06949800

Phase 2, Recruiting
Active & Responsive

Patient Navigation for HER2+ Metastatic Breast Cancer Patients Treated With Tucatinib

for
HER2+ Metastatic Breast Cancer (MBC)
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 18+

Code: NCT06983691

Recruiting
Active & Responsive

Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation

for
Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation,
Location: Boston MA, Chicago IL, Minneapolis MN, Los Angeles CA
Sponsor: Institut de Recherches Internationales Servier (I.R.I.S.)

Sex: All

Age: 12 - 17

Code: NCT07286292

Phase 2, Recruiting
Active & Responsive

Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients

for
Colorectal Cancer
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT07403981

Recruiting
Active & Responsive

UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML

for
Acute Myeloid Leukemia, Pediatric AML
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 30

Code: NCT07059975

Early Phase 1, Recruiting
Active & Responsive

Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors

for
Periampullary Neoplasms, Pancreatic Cancer,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07360119

Recruiting
Active & Responsive

Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis

for
Prostate Cancer Screening
Location: Durham NC, Hardeeville SC
Sponsor: Uro-1 Medical

Sex: Male

Age: 18+

Code: NCT06830265

Recruiting
Active & Responsive

Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma

for
Uveal Melanoma
Location: Philadelphia PA, Toronto, Nashville TN, Scottsdale AZ
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07804186

Phase 3, Recruiting
Active & Responsive

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma,
Location: Washington D.C. DC
Sponsor: Children's National Research Institute

Sex: All

Age: 3 - 25

Code: NCT07664176

Phase 1, Recruiting
Active & Responsive

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07795749

Phase 2, Recruiting
Active & Responsive

Venetoclax Plus Zanubrutinib for the Treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Columbus OH
Sponsor: Kerry Rogers

Sex: All

Age: 18+

Code: NCT07734038

Phase 2, Recruiting