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Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

for
Solid Tumor, Adult, Metastatic Solid Tumor, Refractory Cancer,
Location: Fairfax VA, Canton OH, Detroit MI, St Louis MO
Sponsor: Sairopa B.V.

Sex: All

Age: 18+

Code: NCT05856981

Phase 1, Recruiting

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

for
Advanced Solid Tumor, Refractory Hodgkin Lymphoma
Location: Greenville SC
Sponsor: FBD Biologics Limited

Sex: All

Age: 18+

Code: NCT06487624

Phase 1, Recruiting

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

for
Refractory Cancer, Recurrent Cancer, Solid Tumor, Adult, Cancer
Location: Boston MA, New York NY, Philadelphia PA, Miami FL,
Sponsor: Immatics US, Inc.

Sex: All

Age: 18+

Code: NCT03686124

Phase 1, Phase 2, Recruiting

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer or Malignant Peritoneal Mesothelioma

for
Mesothelin Positive, Mesothelin-Expressing Tumors,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06623396

Phase 1, Recruiting

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

for
Metastatic Bladder Urothelial Carcinoma,
Location: Chicago IL, Orland Park IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT06630416

Phase 2, Recruiting

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Genetic Testing for the Prevention of Cancer in American Indian Communities (JUNIPER Trial)

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06569316

Recruiting

Imaging of Solid Tumors Using FAP-2286

for
Solid Tumors, Adult, Metastatic Cancer
Location: San Francisco CA
Sponsor: Thomas Hope

Sex: All

Age: 18+

Code: NCT04621435

Phase 1, Recruiting

Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

for
Lung Non-Small Cell Carcinoma, Malignant Solid Neoplasm,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05830058

Phase 2, Recruiting

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

for
Metastatic Disease, Primary Tumor, Solid Malignancies
Location: Cincinnati OH
Sponsor: Roshni Dasgupta

Sex: All

Age: 0 - 45

Code: NCT04492735

Recruiting

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

for
Cancer, All Types, Cancer of Liver, Cancer of Stomach,
Location: Gainesville GA
Sponsor: SpeciCare

Sex: All

Age: 0 - 70+

Code: NCT03896958

Recruiting

International Rare Brain Tumor Registry

for
Astroblastoma, BCOR ITD Sarcoma, CNS Sarcoma,
Location: Washington D.C. DC, Akron OH, Cincinnati OH, Chicago IL,
Sponsor: Children's National Research Institute

Sex: All

Age: 0 - 45

Code: NCT05697874

Recruiting

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

for
Neoplasms, Neoplasm Metastasis,
Location: Houston TX
Sponsor: Shanghai EpimAb Biotherapeutics Co., Ltd.

Sex: All

Age: 18+

Code: NCT05176665

Phase 1, Phase 2, Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

for
Cervical Cancer, Throat Cancer, Oropharynx Cancer, Anal Cancer,
Location: New Brunswick NJ, Bethesda MD
Sponsor: Christian Hinrichs

Sex: All

Age: 18+

Code: NCT05686226

Phase 2, Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

for
Solid Tumor, Advanced Solid Tumor, Solid Tumor, Adult,
Location: Boston MA, Hackensack NJ, Philadelphia PA, Fairfax VA,
Sponsor: NiKang Therapeutics, Inc.

Sex: All

Age: 19+

Code: NCT06586957

Phase 1, Recruiting

PRE-ISPY Phase I/II Oncology Platform Program

for
HER2-positive Breast Cancer, Metastatic Cancer,
Location: Birmingham AL, Chicago IL, Orland Park IL, New Lenox IL,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: All

Age: 18+

Code: NCT05868226

Phase 1, Phase 2, Recruiting

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

for
Advanced Malignancies, Ovarian Cancer, T-cell Lymphoma,
Location: New York NY, Philadelphia PA, Duarte CA
Sponsor: BioInvent International AB

Sex: All

Age: 18+

Code: NCT04752826

Phase 1, Phase 2, Recruiting

Feasibility/Acceptability of Attentional-Control Training in Survivors

for
Pediatric Cancer, Pediatric ALL, Pediatric Brain Tumor,
Location: Washington DC
Sponsor: Children's National Research Institute

Sex: All

Age: 8 - 16

Code: NCT05528939

Recruiting

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: Clasp Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06778863

Phase 1, Recruiting

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

for
Malignant Brain Neoplasm, Malignant Solid Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT06788886

Recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06302621

Phase 1, Recruiting