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Safety of the Herpes Zoster Subunit Vaccine in Lupus

for
Systemic Lupus Erythematosus
Location: New York NY, Oklahoma City OK
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 70+

Code: NCT05559671

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for
Systemic Lupus Erythematosus, Lupus Nephritis
Location: Boston MA, Worcester MA, Montreal, Philadelphia PA,
Sponsor: Cabaletta Bio

Sex: All

Age: 18 - 65

Code: NCT06121297

Phase1, Phase2, Recruiting

REACT-01: Reversing Autoimmunity Through Cell Therapy

for
Systemic Lupus Erythematosus
Location: Seattle WA
Sponsor: Seattle Children's Hospital

Sex: All

Age: 2 - 30

Code: NCT06465147

Phase1, Recruiting

At the Heart of the Matter - Speckle Tracking Echocardiography in Lupus Mothers and Their Offspring

for
Systemic Lupus Erythematosus,
Location: Montreal
Sponsor: Evelyne Vinet

Sex: Female

Age: 18 - 45

Code: NCT05451277

Recruiting

Hydroxychloroquine in Systemic Lupus Erythematosus

for
Systemic Lupus Erythematosus
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18+

Code: NCT03802188

Recruiting

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A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

for
Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV),
Location: New York NY, Philadelphia PA, Durham NC, Miami FL,
Sponsor: Fate Therapeutics

Sex: All

Age: 12 - 70

Code: NCT06308978

Phase1, Recruiting

Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease

for
Systemic Lupus Erythematosus
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 20+

Code: NCT00188188

Recruiting

Evaluation of Belimumab Impact on a BLyS Activity Signature Test in the Absence of Confounding Polypharmacy

for
Systemic Lupus Erythematosus
Location: Oklahoma City OK
Sponsor: Oklahoma Medical Research Foundation

Sex: All

Age: 16 - 70

Code: NCT02270970

Recruiting

Pembrolizumab/Lenvatinib With and Without Healthy Donor FMT (hdFMT) in Relapsed/ Refractory (R/R) Melanoma

for
PD-1 Refractory Advanced Melanoma
Location: Pittsburgh PA
Sponsor: Diwakar Davar

Sex: All

Age: 18+

Code: NCT06030037

Phase2, Recruiting

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

for
Lupus Nephritis
Location: New York NY, Hackensack NJ, Chapel Hill NC,
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 8 - 20

Code: NCT05538208

Phase2, Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

for
SLE (Systemic Lupus), Lupus Erythematosus, Systemic,
Location: Boston MA, Chapel Hill NC, Chicago IL, New Orleans LA,
Sponsor: CRISPR Therapeutics

Sex: All

Age: 18 - 70

Code: NCT06925542

Phase1, Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

for
Lupus Nephritis
Location: Queens NY, Hackensack NJ, Montreal, Toronto, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 5 - 17

Code: NCT05039619

Phase2, Recruiting

Trial of Belimumab in Early Lupus

for
Lupus Erythematosus, Systemic, Lupus Erythematosus
Location: Manhasset NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT03543839

Recruiting

A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)

for
Lupus Nephritis, Primary Membranous Nephropathy
Location: Worcester MA, New York NY, Summit NJ, Syracuse NY,
Sponsor: Nkarta, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06557265

Phase1, Phase2, Recruiting

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

for
Lupus Nephritis
Location: Baltimore MD, Charlotte NC, Columbus OH, Hixson TN
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06527872

Recruiting

VIBRANT: VIB4920 for Active Lupus Nephritis

for
Lupus Nephritis
Location: New Haven CT, Manhasset NY, New York NY,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18+

Code: NCT05201469

Phase2, Recruiting

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

for
Lupus Nephritis
Location: Boston MA, East Setauket NY, Philadelphia PA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT05268289

Phase2, Recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

for
IgA Nephropathy, Lupus Nephritis (LN),
Location: Lawrenceville GA
Sponsor: Akebia Therapeutics

Sex: All

Age: 16+

Code: NCT06419205

Phase2, Recruiting

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

for
SLE (Systemic Lupus), RA - Rheumatoid Arthritis
Location: Apple Valley CA, Temecula CA, Riverside CA, Covina CA,
Sponsor: Neutrolis

Sex: All

Age: 18 - 70+

Code: NCT07237659

Phase1, Recruiting

Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous

for
Systemic Lupus Erthematosus (SLE)
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT07713940

Recruiting