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Active & Responsive

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

for
Alcohol Use Disorder
Location: Philadelphia PA, Durham NC, Orlando FL, Cleveland OH,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18 - 70+

Code: NCT07218354

Phase3, Recruiting
Active & Responsive

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

for
Stuttering, Developmental, Dyslexia, Healthy Participants
Location: Boston MA
Sponsor: Boston University Charles River Campus

Sex: All

Age: 18 - 50

Code: NCT07459803

Recruiting
Active & Responsive

A Study of LY4005130 in Adult Participants With Severe Alopecia Areata (Hair Loss)

for
Alopecia Areata
Location: Portsmouth NH, Boston MA, Ottawa, Cutler Bay FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 50

Code: NCT07533006

Phase2, Recruiting
Active & Responsive

Human Laboratory Study of Apremilast for Alcohol Use Disorder

for
Alcohol Use Disorder, Alcohol Misuse
Location: Charlottesville VA, Aurora CO, Los Angeles CA
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All

Age: 21+

Code: NCT07325266

Phase2, Recruiting
Active & Responsive

A Study to Assess the Safety of ARGX-124 in Healthy Volunteers

for
Healthy Volunteers
Location: Montreal
Sponsor: argenx

Sex: All

Age: 18 - 65

Code: NCT07377396

Phase1, Recruiting

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Active & Responsive

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for
Plaque Psoriasis
Location: Boston MA, Cromwell CT, Quebec, New York NY, Montreal,
Sponsor: Oruka Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07449702

Phase2, Recruiting
Active & Responsive

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

for
Depressive Disorder, Major
Location: Boston MA, Watertown MA, Foxborough MA, Levis,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07412756

Phase3, Recruiting
Active & Responsive

The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.

for
Hypertension
Location: Houston TX
Sponsor: Texas Southern University

Sex: All

Age: 55+

Code: NCT07413159

Recruiting
Active & Responsive

Clofutriben Pharmacokinetics in Patients With Impaired Renal Function

for
Moderate Renal Impairment
Location: Orlando FL
Sponsor: Sparrow Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07227922

Phase1, Recruiting
Active & Responsive

A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster.

for
Herpes Zoster (HZ), Vascular Dementia
Location: Webster TX, Houston TX
Sponsor: Center for Clinical Studies, Texas

Sex: All

Age: 18+

Code: NCT06903078

Recruiting
Active & Responsive

Chronic Infections and Inflammation in ME/CFS: An Observational Study

for
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT07227441

Recruiting
Active & Responsive

Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment

for
Obesity & Overweight
Location: Providence RI
Sponsor: The Miriam Hospital

Sex: All

Age: 18 - 70

Code: NCT07228130

Recruiting
Active & Responsive

Rutgers University Study of the Genetics of Pulmonary Hypertension

for
Pulmonary Hypertension, Pulmonary Arterial Hypertension,
Location: Piscataway NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT07217522

Recruiting
Active & Responsive

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

for
Acute HIV Infection
Location: Columbus OH, Atlanta GA, Birmingham AL, Houston TX,
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 70

Code: NCT05719441

Phase2, Recruiting
Active & Responsive

To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Philadelphia PA, Virginia Beach VA, Burke VA, Miami FL,
Sponsor: Expedition Therapeutics, Inc

Sex: All

Age: 40 - 70+

Code: NCT07684820

Phase2, Recruiting
Active & Responsive

Motiva Implants® Post-Approval Study

for
Breast Implant
Location: Hauppauge NY, Sea Girt NJ, New York NY, Cherry Hill NJ,
Sponsor: Motiva USA LLC

Sex: Female

Age: 22+

Code: NCT06938399

Recruiting
Active & Responsive

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

for
Bipolar II Disorder,
Location: San Francisco CA
Sponsor: Andrew Krystal

Sex: All

Age: 22 - 70

Code: NCT07127913

Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

Precision Analytic Research Methods in OCD

for
Obsessive Compulsive Disorder
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18 - 55

Code: NCT07011901

Recruiting
Active & Responsive

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

for
Type 1 Diabetes Mellitus,
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18 - 60

Code: NCT06609356

Early_phase1, Recruiting