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Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact Lenses

for
Myopia
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 18 - 38

Code: NCT07840209

Recruiting
New

Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use

for
Opioid Use, Substance Use Disorders, Opioid Analgesia
Location: Houston TX
Sponsor: Christopher D. Verrico

Sex: All

Age: 18 - 55

Code: NCT07218549

Phase1, Recruiting
Active & ResponsiveNew

Developing New Ways to Detect Respiratory Impairment Early in ALS

for
Amyotrophic Lateral Sclerosis (ALS)
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT07844590

Recruiting
Active & ResponsiveNew

ACT for Dementia Caregivers: Evaluating Psychological Flexibility as the Mechanism to Improve Psychological Distress

for
Dementia Caregivers
Location: Logan UT
Sponsor: Utah State University

Sex: All

Age: 18+

Code: NCT07845032

Recruiting
New

A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult Volunteers

for
Healthy Volunteers
Location: Grayslake IL
Sponsor: AbbVie

Sex: All

Age: 18 - 65

Code: NCT07843693

Phase1, Recruiting

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Active & ResponsiveNew

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)

for
Diabetic Retinopathy, Macular Edema
Location: Charleston SC
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07705607

Phase3, Recruiting
New

Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy

for
Lumbosacral Radiculopathy
Location: Katy TX
Sponsor: Vertanical GmbH

Sex: All

Age: 18+

Code: NCT06956014

Phase3, Recruiting
Active & ResponsiveNew

An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin

for
Pain
Location: McAllen TX
Sponsor: Adneuris Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07845071

Phase3, Recruiting
New

Low-Dose Sirolimus for the Treatment of RUNX1 Familial Platelet Disorder

for
Familial Platelet Disorder With Associated Myeloid Malignancy
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07844694

Early_phase1, Recruiting
New

Velocity-Loss Training and Parkinson's Disease

for
Activity, Motor
Location: Coral Gables FL
Sponsor: University of Miami

Sex: All

Age: 50 - 70+

Code: NCT07840508

Recruiting
New

Older Breast Cancer Patients: Risk for Cognitive Decline

for
Cancer, Breast, Age-related Cognitive Decline,
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: Female

Age: 60 - 70+

Code: NCT03451383

Recruiting
New

Diabetes, Insulin, Gut, Enteric Supplementation Trial

for
Gestational Diabetes Mellitus (GDM), Blood Glucose,
Location: Fredericton
Sponsor: University of New Brunswick

Sex: Female

Age: 19+

Code: NCT07682077

Recruiting
New

Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease

for
Preclinical Alzheimer's Disease
Location: Nashville TN
Sponsor: NewAmsterdam Pharma

Sex: All

Age: 55 - 70+

Code: NCT07794670

Phase2, Recruiting
New

CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)

for
Angelman Syndrome
Location: Carrboro NC
Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All

Age: 2 - 50

Code: NCT07782827

Phase3, Recruiting
New

Feeding the Flame, One Day at a Time: Design and Acceptability of a Serious Game to Support Medication Adherence and Education for Pediatric Solid Organ Transplant Patients

for
Solid Organ Transplant
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 7 - 17

Code: NCT07609303

Recruiting
New

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

for
Overweight, Obesity
Location: Cumberland RI, New York NY, Newport News VA,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT07720271

Phase3, Recruiting
New

Investigation of Egg Intake and the Relationship Between Gut Microbiome, Metabolic, and Immune Profiles

for
Obesity (BMI Equal to or >30), Immune Function, HDL,
Location: Storrs CT
Sponsor: University of Connecticut

Sex: All

Age: 18 - 50

Code: NCT07844616

Recruiting
New

Study to Understand Relationship Between Gut Health and Toxicities of Hormonal Breast Cancer Treatment

for
Breast Cancer
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07553234

Recruiting
New

Early Cognitive Behavioral Therapy for Insomnia (CBT-I) in People Planning to Under Hematopoietic Stem Cell Transplant (HSCT)

for
Hematopoietic Stem Cell Transplant
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT07774039

Phase1, Recruiting
Active & ResponsiveNew

Wellness in PSP and CBD

for
Progressive Supranuclear Palsy, Corticobasal Degeneration
Location: Vancouver
Sponsor: Silke Cresswell

Sex: All

Age: 19+

Code: NCT07844655

Recruiting